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2
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本文引用的文献

1
Biomorphic Ceramics for Drug Delivery in Bone Tissue Regeneration.用于骨组织再生中药物输送的仿生陶瓷
Curr Pharm Des. 2017;23(24):3507-3514. doi: 10.2174/1381612823666170516145309.
2
Porous biomorphic silicon carbide ceramics coated with hydroxyapatite as prospective materials for bone implants.涂覆有羟基磷灰石的多孔生物形态碳化硅陶瓷作为骨植入物的潜在材料。
Mater Sci Eng C Mater Biol Appl. 2016 Nov 1;68:143-152. doi: 10.1016/j.msec.2016.05.113. Epub 2016 May 26.
3
Silicon carbide: a versatile material for biosensor applications.碳化硅：一种用于生物传感器应用的多功能材料。
Biomed Microdevices. 2013 Apr;15(2):353-68. doi: 10.1007/s10544-013-9742-3.
4
Enhanced biological performance of human adipose-derived stem cells cultured on titanium-based biomaterials and silicon carbide sheets for orthopaedic applications.用于骨科应用的基于钛的生物材料和碳化硅片上培养的人脂肪来源干细胞的增强生物学性能。
J Biol Regul Homeost Agents. 2011 Apr-Jun;25(2 Suppl):S35-42.
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Dietary aluminosilicate supplement enhances immune activity in mice and reinforces clearance of porcine circovirus type 2 in experimentally infected pigs.膳食铝硅酸盐补充剂增强了小鼠的免疫活性，并增强了实验感染猪中猪圆环病毒 2 的清除。
Vet Microbiol. 2010 Jul 14;143(2-4):117-25. doi: 10.1016/j.vetmic.2009.11.009. Epub 2009 Dec 22.
6
NO-loaded Zn(2+)-exchanged zeolite materials: a potential bifunctional anti-bacterial strategy.无负载 Zn(2+)-交换沸石材料：一种潜在的双功能抗菌策略。
Acta Biomater. 2010 Apr;6(4):1515-21. doi: 10.1016/j.actbio.2009.10.038. Epub 2009 Oct 25.
7
Biocompatibility of corrosion-resistant zeolite coatings for titanium alloy biomedical implants.用于钛合金生物医学植入物的耐腐蚀沸石涂层的生物相容性
Acta Biomater. 2009 Oct;5(8):3265-71. doi: 10.1016/j.actbio.2009.04.019. Epub 2009 May 4.
8
Role of surface charge and wettability on early stage mineralization and bone cell-materials interactions of polarized hydroxyapatite.表面电荷和润湿性对极化羟基磷灰石早期矿化及骨细胞-材料相互作用的作用
Acta Biomater. 2009 Jul;5(6):2178-88. doi: 10.1016/j.actbio.2009.02.023. Epub 2009 Feb 20.
9
The gene-expression and phenotypic response of hFOB 1.19 osteoblasts to surface-modified titanium and zirconia.人永生化成骨细胞系hFOB 1.19对表面改性钛和氧化锆的基因表达及表型反应
Biomaterials. 2009 Feb;30(6):979-90. doi: 10.1016/j.biomaterials.2008.10.054. Epub 2008 Nov 22.
10
Bioactive, luminescent and mesoporous europium-doped hydroxyapatite as a drug carrier.具有生物活性、发光性和介孔的铕掺杂羟基磷灰石作为药物载体。
Biomaterials. 2008 Nov;29(32):4341-7. doi: 10.1016/j.biomaterials.2008.07.042. Epub 2008 Aug 19.

硅沸石-1/碳化硅泡沫和ZSM-5/碳化硅泡沫都可作为新型骨替代材料。

Both silicalite-1/SiC foam and ZSM-5/SiC foam may serve as novel bone replacement materials.

作者信息

Hao Fengyu, Zhang Cuicui, Wu Lin, Gao Yong, Jiao Yilai

机构信息

Department of Dental Materials, School of Stomatology, China Medical University, Shenyang 110001, China.

Department of Prosthodontics, School of Stomatology, China Medical University, Shenyang 110001, China.

出版信息

Ann Transl Med. 2019 Jun;7(12):255. doi: 10.21037/atm.2019.05.06.

DOI:10.21037/atm.2019.05.06
PMID:31355222
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6614326/
Abstract

BACKGROUND

This study aimed to analyze the bioactivity and biocompatibility of silicon carbide (SiC) foam coated with one of two kinds of zeolite.

METHODS

The surface charges, protein adsorption ability and mineralization ability were compared between silicalite-1/SiC foam and ZSM-5/SiC foam.

RESULTS

Proliferation and differentiation of primary osteoblasts seeded on two types of materials were significantly higher when compared with uncoated SiC foam after 7 d. There was no significant difference in the bioactivity between silicalite-1/SiC foam and ZSM-5/SiC foam. Silicalite-1/SiC foam and ZSM-5/SiC foam had no cytotoxic effect on primary osteoblasts.

CONCLUSIONS

These results suggest both silicalite-1/SiC foam and ZSM-5/SiC foam have the potential for use as novel bone replacement materials.

摘要

背景

本研究旨在分析涂覆有两种沸石之一的碳化硅（SiC）泡沫的生物活性和生物相容性。

方法

比较了硅沸石-1/SiC泡沫和ZSM-5/SiC泡沫之间的表面电荷、蛋白质吸附能力和矿化能力。

结果

与未涂层的SiC泡沫相比，接种在两种材料上的原代成骨细胞在7天后的增殖和分化明显更高。硅沸石-1/SiC泡沫和ZSM-5/SiC泡沫之间的生物活性没有显著差异。硅沸石-1/SiC泡沫和ZSM-5/SiC泡沫对原代成骨细胞没有细胞毒性作用。

结论

这些结果表明，硅沸石-1/SiC泡沫和ZSM-5/SiC泡沫都有潜力用作新型骨替代材料。