硅沸石-1/碳化硅泡沫和ZSM-5/碳化硅泡沫都可作为新型骨替代材料。
Both silicalite-1/SiC foam and ZSM-5/SiC foam may serve as novel bone replacement materials.
作者信息
Hao Fengyu, Zhang Cuicui, Wu Lin, Gao Yong, Jiao Yilai
机构信息
Department of Dental Materials, School of Stomatology, China Medical University, Shenyang 110001, China.
Department of Prosthodontics, School of Stomatology, China Medical University, Shenyang 110001, China.
出版信息
Ann Transl Med. 2019 Jun;7(12):255. doi: 10.21037/atm.2019.05.06.
BACKGROUND
This study aimed to analyze the bioactivity and biocompatibility of silicon carbide (SiC) foam coated with one of two kinds of zeolite.
METHODS
The surface charges, protein adsorption ability and mineralization ability were compared between silicalite-1/SiC foam and ZSM-5/SiC foam.
RESULTS
Proliferation and differentiation of primary osteoblasts seeded on two types of materials were significantly higher when compared with uncoated SiC foam after 7 d. There was no significant difference in the bioactivity between silicalite-1/SiC foam and ZSM-5/SiC foam. Silicalite-1/SiC foam and ZSM-5/SiC foam had no cytotoxic effect on primary osteoblasts.
CONCLUSIONS
These results suggest both silicalite-1/SiC foam and ZSM-5/SiC foam have the potential for use as novel bone replacement materials.
背景
本研究旨在分析涂覆有两种沸石之一的碳化硅（SiC）泡沫的生物活性和生物相容性。
方法
比较了硅沸石-1/SiC泡沫和ZSM-5/SiC泡沫之间的表面电荷、蛋白质吸附能力和矿化能力。
结果
与未涂层的SiC泡沫相比，接种在两种材料上的原代成骨细胞在7天后的增殖和分化明显更高。硅沸石-1/SiC泡沫和ZSM-5/SiC泡沫之间的生物活性没有显著差异。硅沸石-1/SiC泡沫和ZSM-5/SiC泡沫对原代成骨细胞没有细胞毒性作用。
结论
这些结果表明，硅沸石-1/SiC泡沫和ZSM-5/SiC泡沫都有潜力用作新型骨替代材料。
Zotero 插件