Poverty, Health and Nutrition Division, International Food Policy Research Institute (IFPRI), Washington, District of Columbia.
Department of Science, Technology and International Cooperation, Thai Nguyen University of Pharmacy and Medicine, Thai Nguyen, Vietnam.
Autism Res. 2019 Nov;12(11):1706-1718. doi: 10.1002/aur.2179. Epub 2019 Jul 29.
The Social Responsiveness Scale (SRS) has been validated in high-income countries but not yet in low- and middle-income countries. We aimed to assess the reliability of the SRS in a community sample and its validity to discriminate between children with and without autism spectrum disorder (ASD) in Vietnam. We used a three-phase study: piloting the translated SRS, reliability testing, and validation of the SRS in 158 Vietnamese caretakers and their children (ages 4-9 years). We examined reliability, validity and sensitivity, and specificity to ASD diagnosis. We applied receiver operator characteristic (ROC) analysis to determine optimal cutoff scores discriminating the children with ASD from those without ASD. We also assessed the performance of the SRS short form. We found that reliability was good with high internal consistency (0.88-0.89), test-retest reliability (0.82-0.83), sensitivity (93%), and specificity (98%) for identification of children with ASD. The ROC curves were similar for total raw score and total T-score, with the area under the curve (AUC) values reaching 0.98 and the optimal cutoff of 62 for raw scores and 60 for T-scores. The SRS short form also performed well in distinguishing children with ASD from children without ASD, with high AUC (0.98), sensitivity (90%), and specificity (98%) when using a raw score of 15 as a cutoff. In conclusion, the translated and culturally adapted SRS shows good reliability, validity, and sensitivity for identification of children with ASD in Vietnam. Both SRS long and short forms performed adequately to discriminate between children with and without ASD. Autism Res 2019, 00: 1-13. © 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Middle-income countries often lack validated tools to evaluate autism symptoms. The Social Responsiveness Scale (SRS) translated to Vietnamese was reliable and performed well to distinguish between children with and without autism spectrum disorder in Vietnam. The Vietnamese SRS, and translations of the tool to other languages with this methodology, may be useful in pediatric practice, potentially allowing providers to make more appropriate referrals for diagnostic evaluations and identify children for intervention to help them fulfill their developmental potential.
社会反应量表（SRS）已在高收入国家得到验证，但尚未在中低收入国家得到验证。我们旨在评估 SRS 在社区样本中的可靠性及其区分越南有无自闭症谱系障碍（ASD）儿童的有效性。我们使用了三阶段研究：翻译 SRS 的试点、可靠性测试以及对 158 名越南照顾者及其 4-9 岁儿童的 SRS 验证。我们检查了可靠性、有效性和灵敏度以及对 ASD 诊断的特异性。我们应用接收器操作特性（ROC）分析来确定区分 ASD 儿童和非 ASD 儿童的最佳截断分数。我们还评估了 SRS 短表的性能。我们发现，信度良好，内部一致性高（0.88-0.89），测试-重测信度（0.82-0.83），对识别自闭症儿童的敏感性（93%）和特异性（98%）。总原始分数和总 T 分数的 ROC 曲线相似，曲线下面积（AUC）值分别为 0.98，原始分数的最佳截断值为 62，T 分数为 60。SRS 短表在区分自闭症儿童和非自闭症儿童方面也表现良好，使用 15 分作为截断值时，AUC（0.98）、敏感性（90%）和特异性（98%）均较高。总之，翻译后的 SRS 在越南具有良好的可靠性、有效性和敏感性，可用于识别自闭症儿童。SRS 长表和短表在区分自闭症儿童和非自闭症儿童方面表现良好。自闭症研究 2019 年，00 期：1-13. © 2019 国际自闭症研究协会，威利在线期刊，公司。
