Wulf H C, Bech-Thomsen N
Department of Dermatology and Venereology, Rigshospital, Copenhagen, Denmark.
Sex Transm Dis. 1988 Apr-Jun;15(2):116-8. doi: 10.1097/00007435-198804000-00011.
The efficacy of three different regimens of oral medication for pharyngeal gonorrhea was examined in a study of 119 patients. Of 34 patients treated with 1.4 g of pivampicillin plus 1.0 g of probenecid, both taken once a day for five days, 33 (97.1%) were cured. The other two regimens consisted of tablets containing sulfamethoxazole (400 mg) and trimethoprim (80 mg). Of 36 patients treated with a single ten-tablet dose on the first day, two five-tablet doses on the second day, and two three-tablet doses for the next three to five days, 35 (97.2%) were cured. Of 49 patients treated with a single ten-tablet dose on the first day and two five-tablet doses on the second day, 44 (89.8%) were cured. The cure rates for the three regimens were not significantly different (P greater than 0.05). Therefore, we conclude that a two-day trimethoprim-sulfamethoxazole regimen is quick, inexpensive, and reliable in the treatment of pharyngeal gonorrhea.
在一项针对119名患者的研究中，对三种不同口服药物治疗咽部淋病的疗效进行了检查。34名患者接受1.4克匹氨西林加1.0克丙磺舒治疗，均每日服用一次，连服五天，其中33例（97.1%）治愈。另外两种治疗方案为含磺胺甲恶唑（400毫克）和甲氧苄啶（80毫克）的片剂。36名患者在第一天服用一次十片剂量，第二天服用两次五片剂量，接下来三至五天每天服用两次三片剂量，其中35例（97.2%）治愈。49名患者在第一天服用一次十片剂量，第二天服用两次五片剂量，其中44例（89.8%）治愈。三种治疗方案的治愈率无显著差异（P大于0.05）。因此，我们得出结论，两天的甲氧苄啶-磺胺甲恶唑治疗方案治疗咽部淋病快速、廉价且可靠。
