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[肝硬化与肝癌癌前病变的研究进展]

[Advances in the study of cirrhosis and precancerous lesions of liver cancer].

作者信息

Wu D B, Tang H

机构信息

Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China.

出版信息

Zhonghua Gan Zang Bing Za Zhi. 2019 Jul 20;27(7):483-486. doi: 10.3760/cma.j.issn.1007-3418.2019.07.002.

Abstract

Liver cirrhosis is a common kind of chronic liver diseases, with the development of diseases; some patients may gradually develop precancerous lesions, or even progress to hepatocellular carcinoma (HCC). Precancerous lesions of the liver mainly include dysplastic foci (DF) and dysplastic nodules (DN), and most of it occurs on the basis of liver cirrhosis. Thus, recognition of precancerous lesions and liver cirrhosis through screening, combined with imaging and pathological features will identity the nature of nodules in early stage cirrhosis and HCC, and thereby will help to improve the diagnosis rate and clinical prognosis.

摘要

肝硬化是一种常见的慢性肝病,随着疾病的发展,一些患者可能会逐渐发展为癌前病变,甚至进展为肝细胞癌(HCC)。肝脏的癌前病变主要包括发育异常灶(DF)和发育异常结节(DN),且大多发生在肝硬化的基础上。因此,通过筛查结合影像学和病理特征来识别癌前病变和肝硬化,将有助于明确早期肝硬化和HCC结节的性质,从而提高诊断率和临床预后。

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