School of Information Engineering, Guangdong Medical University, Zhanjiang, 524023, China.
School of Basic Medical Science, Guangdong Medical University, Zhanjiang, 524023, China.
Sci Rep. 2019 Jul 29;9(1):10971. doi: 10.1038/s41598-019-47281-7.
Considering the poor medical conditions in some regions of China, this paper attempts to develop a simple and easy way to extract and process the bone features of blurry medical images and improve the diagnosis accuracy of osteoporosis as much as possible. After reviewing the previous studies on osteoporosis, especially those focusing on texture analysis, a convexity optimization model was proposed based on intra-class dispersion, which combines texture features and shape features. Experimental results show that the proposed model boasts a larger application scope than Lasso, a popular feature selection method that only supports generalized linear models. The research findings ensure the accuracy of osteoporosis diagnosis and enjoy good potentials for clinical application.
考虑到中国部分地区医疗条件较差,本文尝试开发一种简单易用的方法来提取和处理模糊医学图像的骨骼特征,尽可能提高骨质疏松症的诊断准确率。在回顾了之前关于骨质疏松症的研究,特别是那些关注纹理分析的研究之后,本文提出了一种基于类内离散度的凸优化模型,该模型结合了纹理特征和形状特征。实验结果表明,与仅支持广义线性模型的流行特征选择方法 Lasso 相比,所提出的模型具有更大的应用范围。研究结果确保了骨质疏松症诊断的准确性,并具有良好的临床应用潜力。