Graduate School of Public Health, Teikyo University, Tokyo, Japan.
Department of Health and Social Behaviour, School of Public Health, The University of Tokyo, Tokyo, Japan.
Sci Rep. 2019 Jul 29;9(1):10936. doi: 10.1038/s41598-019-47448-2.
The purpose of this study was to examine the association between employment status and adiponectin levels. This cross-sectional study was a part of the Japanese Stratification, Health, Income, and Neighborhood study, a population-based survey in metropolitan Japan. The analysis included data from 848 individuals. A one-way analysis of variance was used to assess differences in log-transformed adiponectin levels among individuals according to their employment status. Multiple linear regression analysis was used to assess these differences after adjusting for other cardiovascular disease risk factors. The main outcome was log-transformed adiponectin. Of the participants, 6.2% of the men and 15.1% of the women were precarious workers. Mean adiponectin values differed significantly by employment status in men, but not in women. In men, multiple regression analysis showed that precarious workers had significantly lower adiponectin levels than permanent workers (β = -0.16, P = 0.02). However, in women, adiponectin levels were significantly lower only in precarious workers with low household incomes (β = -0.35, P = 0.02). Male precarious workers and their female counterparts with low annual household incomes had significantly lower levels of adiponectin. These results might help us to understand mechanisms underlying the relationship between employment status and cardiovascular disease.
这项研究的目的是探讨就业状况与脂联素水平之间的关系。这是一项横断面研究，是日本分层、健康、收入和邻里研究的一部分，该研究是日本大都市地区的一项基于人群的调查。分析包括了 848 名个体的数据。采用单因素方差分析评估了根据就业状况不同，个体的对数转换脂联素水平的差异。采用多元线性回归分析在调整了其他心血管疾病危险因素后评估了这些差异。主要结局是对数转换的脂联素。在参与者中，男性中有 6.2%是不稳定工人，女性中有 15.1%是不稳定工人。男性的平均脂联素值根据就业状况存在显著差异，但女性则没有。在男性中，多元回归分析显示，不稳定工人的脂联素水平明显低于固定工人（β=-0.16，P=0.02）。然而，在女性中，只有收入较低的不稳定工人的脂联素水平显著降低（β=-0.35，P=0.02）。男性不稳定工人及其收入较低的女性对应者的脂联素水平明显降低。这些结果可能有助于我们理解就业状况与心血管疾病之间关系的潜在机制。
