Medical Oncology, Complejo Hospitalario de Navarra, Calle Irunlarrea, 3, 31008, Pamplona, Navarra, Spain.
Medical Oncology, Hospital Virgen de Las Nieves, Granada, Spain.
Clin Transl Oncol. 2020 May;22(5):647-662. doi: 10.1007/s12094-019-02182-z. Epub 2019 Jul 29.
Colorectal cancer (CRC) has the second-highest tumor incidence and is a leading cause of death by cancer. Nearly 20% of patients with CRC will have metastases at the time of diagnosis, and more than 50% of patients with CRC develop metastatic disease during the course of their disease. A group of experts from the Spanish Society of Medical Oncology, the Spanish Association of Surgeons, the Spanish Society of Radiation Oncology, the Spanish Society of Vascular and Interventional Radiology, and the Spanish Society of Nuclear Medicine and Molecular Imaging met to discuss and provide a multidisciplinary consensus on the management of liver metastases in patients with CRC. The group defined the different scenarios in which the disease can present: fit or unfit patients with resectable liver metastases, patients with potential resectable liver metastases, and patients with unresectable liver metastases. Within each scenario, the different strategies and therapeutic approaches are discussed.
结直肠癌(CRC)的肿瘤发病率位居第二,是癌症死亡的主要原因之一。近 20%的 CRC 患者在诊断时已有转移,超过 50%的 CRC 患者在疾病过程中发生转移性疾病。西班牙肿瘤医学学会、西班牙外科医师学会、西班牙放射肿瘤学会、西班牙血管和介入放射学学会以及西班牙核医学和分子影像学学会的一组专家开会讨论并就 CRC 患者肝转移的管理提供了多学科共识。该小组定义了疾病可能出现的不同情况:可切除肝转移的适宜或不适宜患者、有潜在可切除肝转移的患者和不可切除肝转移的患者。在每种情况下,都讨论了不同的策略和治疗方法。