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结直肠癌肝转移多学科综合管理:西班牙肿瘤学会、西班牙放射肿瘤学会、西班牙肿瘤外科学会、西班牙肿瘤内科学会和西班牙核医学与分子影像学会共识。

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM.

机构信息

Medical Oncology, Complejo Hospitalario de Navarra, Calle Irunlarrea, 3, 31008, Pamplona, Navarra, Spain.

Medical Oncology, Hospital Virgen de Las Nieves, Granada, Spain.

出版信息

Clin Transl Oncol. 2020 May;22(5):647-662. doi: 10.1007/s12094-019-02182-z. Epub 2019 Jul 29.

DOI:10.1007/s12094-019-02182-z
PMID:31359336
Abstract

Colorectal cancer (CRC) has the second-highest tumor incidence and is a leading cause of death by cancer. Nearly 20% of patients with CRC will have metastases at the time of diagnosis, and more than 50% of patients with CRC develop metastatic disease during the course of their disease. A group of experts from the Spanish Society of Medical Oncology, the Spanish Association of Surgeons, the Spanish Society of Radiation Oncology, the Spanish Society of Vascular and Interventional Radiology, and the Spanish Society of Nuclear Medicine and Molecular Imaging met to discuss and provide a multidisciplinary consensus on the management of liver metastases in patients with CRC. The group defined the different scenarios in which the disease can present: fit or unfit patients with resectable liver metastases, patients with potential resectable liver metastases, and patients with unresectable liver metastases. Within each scenario, the different strategies and therapeutic approaches are discussed.

摘要

结直肠癌(CRC)的肿瘤发病率位居第二,是癌症死亡的主要原因之一。近 20%的 CRC 患者在诊断时已有转移,超过 50%的 CRC 患者在疾病过程中发生转移性疾病。西班牙肿瘤医学学会、西班牙外科医师学会、西班牙放射肿瘤学会、西班牙血管和介入放射学学会以及西班牙核医学和分子影像学学会的一组专家开会讨论并就 CRC 患者肝转移的管理提供了多学科共识。该小组定义了疾病可能出现的不同情况:可切除肝转移的适宜或不适宜患者、有潜在可切除肝转移的患者和不可切除肝转移的患者。在每种情况下,都讨论了不同的策略和治疗方法。

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BMC Cancer. 2018 Aug 15;18(1):821. doi: 10.1186/s12885-018-4716-8.
2
Genetic And Morphological Evaluation (GAME) score for patients with colorectal liver metastases.结直肠癌肝转移患者的遗传和形态学评估(GAME)评分。
Br J Surg. 2018 Aug;105(9):1210-1220. doi: 10.1002/bjs.10838. Epub 2018 Apr 25.
3
Ablation of colorectal liver metastasis: Interaction of ablation margins and RAS mutation profiling on local tumour progression-free survival.
Eastern Canadian Gastrointestinal Cancer Consensus Conference 2024.
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Curr Oncol. 2025 Mar 18;32(3):175. doi: 10.3390/curroncol32030175.
4
Enhancing Anti-PD-1 Immunotherapy by Targeting MDSCs via Hepatic Arterial Infusion in Breast Cancer Liver Metastases.通过肝动脉灌注靶向髓源性抑制细胞增强乳腺癌肝转移中的抗PD-1免疫疗法。
Cancers (Basel). 2024 Nov 3;16(21):3711. doi: 10.3390/cancers16213711.
5
Neoadjuvant Statistical Algorithm to Predict Individual Risk of Relapse in Patients with Resected Liver Metastases from Colorectal Cancer.预测结直肠癌肝转移切除患者个体复发风险的新辅助统计算法
Biomedicines. 2024 Aug 15;12(8):1859. doi: 10.3390/biomedicines12081859.
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Curr Oncol Rep. 2024 Jul;26(7):791-803. doi: 10.1007/s11912-024-01548-z. Epub 2024 May 22.
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Medicina (Kaunas). 2024 Jan 31;60(2):251. doi: 10.3390/medicina60020251.
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