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重新审视2D:4D与雄激素受体(AR)基因及当前睾酮水平的关系:重复研究与荟萃分析。

Revisiting the relationships of 2D:4D with androgen receptor (AR) gene and current testosterone levels: Replication study and meta-analyses.

作者信息

Zhang Kejin, Yang Xing, Zhang Mengfei, Wang Chunlan, Fang Pengpeng, Xue Mengying, Zhao Jing, Gao Xiaocai, Pan Ruliang, Gong Pingyuan

机构信息

Shaanxi Key Laboratory for Animal Conservation, Northwest University, Xi'an, China.

College of Life Science, Northwest University, Xi'an, China.

出版信息

J Neurosci Res. 2020 Feb;98(2):353-370. doi: 10.1002/jnr.24502. Epub 2019 Jul 29.

DOI:10.1002/jnr.24502
PMID:31359506
Abstract

The relationships of digit ratio (2D:4D) with the length of AR (CAG)n, and testosterone levels from saliva and blood have been extensively debated over the years. This research including three studies further clarifies such controversies. To do so, we re-examined the relationships between the length of AR (CAG)n, 2D:4D, and current testosterone levels, through replication study and meta-analysis for each study. The results indicate: (a) the length of AR (CAG)n is not significantly associated with 2D:4D; (b) current testosterone levels are not significantly associated with the ratio; and (c) the length is not significantly associated with testosterone levels. Thus, AR (CAG)n and current testosterone levels are not significantly related to 2D:4D at individual level.

摘要

多年来,手指比例(2D:4D)与雄激素受体(AR)(CAG)n的长度以及唾液和血液中的睾酮水平之间的关系一直存在广泛争议。这项包含三项研究的调查进一步厘清了此类争议。为此,我们通过每项研究的重复研究和荟萃分析,重新审视了AR(CAG)n的长度、2D:4D与当前睾酮水平之间的关系。结果表明:(a)AR(CAG)n的长度与2D:4D无显著关联;(b)当前睾酮水平与该比例无显著关联;(c)AR(CAG)n的长度与睾酮水平无显著关联。因此,在个体层面,AR(CAG)n和当前睾酮水平与2D:4D无显著关系。

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