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唐氏综合征合并心包积液的短暂异常骨髓生成:病例报告

Transient abnormal myelopoiesis with pericardial effusion in Down syndrome: Case report.

作者信息

Falasco Bianca Francisco, Durante Brenda, Faria Daniel Kanaan, Faria Caroline Silvério, Rosolen Débora Cristina Batista, Antonangelo Leila

机构信息

Divisao de Patologia Clinica - Departamento de Patologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina Universidade de Sao Paulo Sao Paulo SP Brazil.

Laboratorio de Investigacao Medica (LIM 03), Faculdade de Medicina FMUSP Universidade de Sao Paulo Sao Paulo SP Brazil.

出版信息

Clin Case Rep. 2019 May 17;7(7):1280-1284. doi: 10.1002/ccr3.2184. eCollection 2019 Jul.

Abstract

Pericardial effusion associated with transient abnormal myelopoiesis in Down's syndrome neonates needs to be diagnosed in a timely manner, and the comorbidities must be treated to prevent mortality. To our knowledge, the occurrence of basophilic/eosinophilic pericardial effusion without an increase of these cells in the peripheral blood and with no evidence of associated hypothyroidism is rare.

摘要

唐氏综合征新生儿中与短暂异常骨髓造血相关的心包积液需要及时诊断,必须治疗合并症以防止死亡。据我们所知,外周血中这些细胞未增多且无相关甲状腺功能减退证据的嗜碱性/嗜酸性心包积液的发生较为罕见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8189/6637340/694e849c028d/CCR3-7-1280-g001.jpg

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