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骨质疏松症对脊柱影响的综述与临床展望

A Review and Clinical Perspective of the Impact of Osteoporosis on the Spine.

作者信息

Carlson Bayard C, Robinson William A, Wanderman Nathan R, Sebastian Arjun S, Nassr Ahmad, Freedman Brett A, Anderson Paul A

机构信息

Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.

出版信息

Geriatr Orthop Surg Rehabil. 2019 Jul 17;10:2151459319861591. doi: 10.1177/2151459319861591. eCollection 2019.

Abstract

INTRODUCTION

Osteopenia and osteoporosis are common conditions in the United States. The health consequences of low bone density can be dire, from poor surgical outcomes to increased mortality rates following a fracture.

SIGNIFICANCE

This article highlights the impact low bone density has on spine health in terms of vertebral fragility fractures and its adverse effects on elective spine surgery. It also reviews the clinical importance of bone health assessment and optimization.

RESULTS

Vertebral fractures are the most common fragility fractures with significant consequences related to patient morbidity and mortality. Additionally, a vertebral fracture is the best predictor of a subsequent fracture. These fractures constitute sentinel events in osteoporosis that require further evaluation and treatment of the patient's underlying bone disease. In addition to fractures, osteopenia and osteoporosis have deleterious effects on elective spine surgery from screw pullout to fusion rates. Adequate evaluation and treatment of a patient's underlying bone disease in these situations have been shown to improve patient outcomes.

CONCLUSION

With an increased understanding of the prevalence of low bone mass and its consequences as well an understanding of how to identify these patients and appropriately intervene, spine surgeons can effectively decrease the rates of adverse health outcomes related to low bone mass.

摘要

引言

骨质减少和骨质疏松在美国是常见病症。骨密度低对健康的影响可能很严重,从手术效果不佳到骨折后死亡率增加。

意义

本文强调了低骨密度在椎体脆性骨折方面对脊柱健康的影响及其对择期脊柱手术的不良影响。它还回顾了骨健康评估和优化的临床重要性。

结果

椎体骨折是最常见的脆性骨折,与患者的发病率和死亡率有重大关联。此外,椎体骨折是后续骨折的最佳预测指标。这些骨折是骨质疏松症中的标志性事件,需要对患者潜在的骨病进行进一步评估和治疗。除了骨折,骨质减少和骨质疏松对择期脊柱手术也有有害影响,从螺钉拔出到融合率。在这些情况下,对患者潜在骨病进行充分评估和治疗已被证明可改善患者预后。

结论

随着对低骨量患病率及其后果的认识增加,以及对如何识别这些患者并进行适当干预的理解,脊柱外科医生可以有效降低与低骨量相关的不良健康结局发生率。

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A Review and Clinical Perspective of the Impact of Osteoporosis on the Spine.骨质疏松症对脊柱影响的综述与临床展望
Geriatr Orthop Surg Rehabil. 2019 Jul 17;10:2151459319861591. doi: 10.1177/2151459319861591. eCollection 2019.
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