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The fate of thoracolumbar surgeries in patients with Parkinson's disease, and analysis of risk factors for revision surgeries.帕金森病患者胸腰椎手术的预后及翻修手术危险因素分析。
BMC Musculoskelet Disord. 2019 Mar 14;20(1):106. doi: 10.1186/s12891-019-2481-8.
2
Effect of osteoporosis on the clinical and radiological outcomes following one-level posterior lumbar interbody fusion.骨质疏松对单节段腰椎后路椎间融合术后临床及影像学结果的影响。
J Orthop Sci. 2018 Nov;23(6):870-877. doi: 10.1016/j.jos.2018.06.009. Epub 2018 Jul 6.
3
Exploratory analysis of predictors of revision surgery for proximal junctional kyphosis or additional postoperative vertebral fracture following adult spinal deformity surgery in elderly patients: a retrospective cohort study.老年患者成人脊柱畸形手术后近端交界性后凸或额外术后椎体骨折翻修手术预测因素的探索性分析:一项回顾性队列研究
J Orthop Surg Res. 2018 Oct 12;13(1):252. doi: 10.1186/s13018-018-0960-5.
4
Incidence of Osteoporosis-Related Complications Following Posterior Lumbar Fusion.腰椎后路融合术后骨质疏松相关并发症的发生率
Global Spine J. 2018 Sep;8(6):563-569. doi: 10.1177/2192568217743727. Epub 2017 Dec 10.
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Hounsfield unit of screw trajectory as a predictor of pedicle screw loosening after single level lumbar interbody fusion.作为单节段腰椎椎间融合术后椎弓根螺钉松动预测指标的螺钉轨迹亨氏单位
J Orthop Sci. 2018 Sep;23(5):734-738. doi: 10.1016/j.jos.2018.04.006. Epub 2018 Jun 14.
6
Practice Patterns and Performance in U.S. Fracture Liaison Programs: An Analysis of >32,000 Patients from the Own the Bone Program.美国骨折联络计划中的实践模式和表现:来自“拥有骨骼”计划的超过 32000 名患者的分析。
J Bone Joint Surg Am. 2018 Apr 18;100(8):680-685. doi: 10.2106/JBJS.17.00665.
7
Comparison of adult spinal deformity patients with and without rheumatoid arthritis undergoing primary non-cervical spinal fusion surgery: a nationwide analysis of 52,818 patients.比较原发性非颈椎脊柱融合手术治疗的成人脊柱畸形患者与类风湿关节炎患者:一项全国性分析 52818 例患者。
Spine J. 2018 Oct;18(10):1861-1866. doi: 10.1016/j.spinee.2018.03.020. Epub 2018 Apr 6.
8
Own the Bone, a System-Based Intervention, Improves Osteoporosis Care After Fragility Fractures.“掌控骨骼”,一种基于系统的干预措施,可改善脆性骨折后的骨质疏松症护理。
J Bone Joint Surg Am. 2016 Dec 21;98(24):e109. doi: 10.2106/JBJS.15.01494.
9
Effect of various factors on pull out strength of pedicle screw in normal and osteoporotic cancellous bone models.各种因素对正常及骨质疏松性松质骨模型中椎弓根螺钉拔出强度的影响。
Med Eng Phys. 2017 Feb;40:28-38. doi: 10.1016/j.medengphy.2016.11.012. Epub 2016 Dec 9.
10
Clinical and Radiographic Outcomes of Transforaminal Lumbar Interbody Fusion in Patients with Osteoporosis.骨质疏松症患者经椎间孔腰椎椎间融合术的临床及影像学结果
Global Spine J. 2016 Nov;6(7):660-664. doi: 10.1055/s-0036-1578804. Epub 2016 Feb 19.

骨质疏松症对脊柱影响的综述与临床展望

A Review and Clinical Perspective of the Impact of Osteoporosis on the Spine.

作者信息

Carlson Bayard C, Robinson William A, Wanderman Nathan R, Sebastian Arjun S, Nassr Ahmad, Freedman Brett A, Anderson Paul A

机构信息

Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.

出版信息

Geriatr Orthop Surg Rehabil. 2019 Jul 17;10:2151459319861591. doi: 10.1177/2151459319861591. eCollection 2019.

DOI:10.1177/2151459319861591
PMID:31360592
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6637832/
Abstract

INTRODUCTION

Osteopenia and osteoporosis are common conditions in the United States. The health consequences of low bone density can be dire, from poor surgical outcomes to increased mortality rates following a fracture.

SIGNIFICANCE

This article highlights the impact low bone density has on spine health in terms of vertebral fragility fractures and its adverse effects on elective spine surgery. It also reviews the clinical importance of bone health assessment and optimization.

RESULTS

Vertebral fractures are the most common fragility fractures with significant consequences related to patient morbidity and mortality. Additionally, a vertebral fracture is the best predictor of a subsequent fracture. These fractures constitute sentinel events in osteoporosis that require further evaluation and treatment of the patient's underlying bone disease. In addition to fractures, osteopenia and osteoporosis have deleterious effects on elective spine surgery from screw pullout to fusion rates. Adequate evaluation and treatment of a patient's underlying bone disease in these situations have been shown to improve patient outcomes.

CONCLUSION

With an increased understanding of the prevalence of low bone mass and its consequences as well an understanding of how to identify these patients and appropriately intervene, spine surgeons can effectively decrease the rates of adverse health outcomes related to low bone mass.

摘要

引言

骨质减少和骨质疏松在美国是常见病症。骨密度低对健康的影响可能很严重,从手术效果不佳到骨折后死亡率增加。

意义

本文强调了低骨密度在椎体脆性骨折方面对脊柱健康的影响及其对择期脊柱手术的不良影响。它还回顾了骨健康评估和优化的临床重要性。

结果

椎体骨折是最常见的脆性骨折,与患者的发病率和死亡率有重大关联。此外,椎体骨折是后续骨折的最佳预测指标。这些骨折是骨质疏松症中的标志性事件,需要对患者潜在的骨病进行进一步评估和治疗。除了骨折,骨质减少和骨质疏松对择期脊柱手术也有有害影响,从螺钉拔出到融合率。在这些情况下,对患者潜在骨病进行充分评估和治疗已被证明可改善患者预后。

结论

随着对低骨量患病率及其后果的认识增加,以及对如何识别这些患者并进行适当干预的理解,脊柱外科医生可以有效降低与低骨量相关的不良健康结局发生率。