Nair Bindu, Taylor-Gjevre Regina, Wu Liying, Jin Shan, Quail Jacqueline M
1College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan Canada.
2Saskatchewan Health Quality Council, Saskatoon, Saskatchewan Canada.
BMC Rheumatol. 2019 Jul 18;3:28. doi: 10.1186/s41927-019-0077-4. eCollection 2019.
Rheumatoid arthritis (RA) is a chronic inflammatory and destructive arthritis. Understanding the incidence and prevalence of RA within the province facilitates appropriate health care resource planning.
To estimate the incidence/prevalence of RA over time for the overall provincial population, for specific age range categories, and for gender.
Saskatchewan Provincial Administrative Health Databases (2001-2014) were utilized as data sources. Two RA case-definitions were employed: 1) > three physician billing diagnoses, at least one of which was submitted by a specialist (rheumatologist, general internist or orthopedic surgeon) within 2 years; 2) > one hospitalization diagnosis (ICD-9-CM code-714, and ICD-10-CA code-M05). Data from these definitions were combined to identify incident and prevalent RA cases. Using this data, annual incidence and prevalence rates were calculated for the provincial population, specified age range categories and gender categories.
The number of RA cases meeting the case definition increased from 3731 to 6223 over the study period. The incidence of RA disease demonstrated variation within the study period with age and sex adjusted incidence ranging from 33.6 (95% CI 29.9-37.6) per 100,000 to 73.1 (95% CI 67.6-79.0) per 100,000. The prevalence of RA increased over time from 482 (95% CI 466.7-497.7) per 100,000 in 2001-2002 to 683.4 (95% CI 666.6-700.6) per 100,000 in 2014-2015. Both incidence and prevalence rates rose with increasing age. Women were found to have higher incidence and prevalence rates compared to men.
In Saskatchewan, the overall prevalence of RA is rising while there has been variability in the incidence.
类风湿性关节炎（RA）是一种慢性炎症性和破坏性关节炎。了解该省类风湿性关节炎的发病率和患病率有助于进行适当的医疗资源规划。
估计该省总体人群、特定年龄范围类别以及不同性别的类风湿性关节炎发病率/患病率随时间的变化情况。
使用萨斯喀彻温省省级行政卫生数据库（2001 - 2014年）作为数据源。采用了两种类风湿性关节炎病例定义：1）超过三次医生计费诊断，其中至少有一次是由专科医生（风湿病学家、普通内科医生或骨科医生）在两年内提交的；2）超过一次住院诊断（ICD - 9 - CM编码714，以及ICD - 10 - CA编码M05）。将这些定义的数据合并以识别类风湿性关节炎的发病病例和患病病例。利用这些数据，计算了该省总体人群、指定年龄范围类别和性别类别的年发病率和患病率。
在研究期间，符合病例定义的类风湿性关节炎病例数从3731例增加到6223例。类风湿性关节炎疾病的发病率在研究期间表现出差异，年龄和性别调整后的发病率范围为每10万人33.6（95%可信区间29.9 - 37.6）至每10万人73.1（95%可信区间67.6 - 79.0）。类风湿性关节炎的患病率随时间从2001 - 2002年的每10万人482（95%可信区间466.7 - 497.7）上升至2014 - 2015年的每10万人683.4（95%可信区间666.6 - 700.6）。发病率和患病率均随年龄增长而上升。发现女性的发病率和患病率高于男性。
在萨斯喀彻温省，类风湿性关节炎的总体患病率在上升，而发病率存在差异。
