Palomo Jose M
Department of Biocatalysis, Institute of Catalysis (CSIC), Marie Curie 2, Cantoblanco, UAM Campus, 28049, Madrid, Spain.
Chem Commun (Camb). 2019 Aug 21;55(65):9583-9589. doi: 10.1039/c9cc04944d. Epub 2019 Jul 30.
In recent years, nanoscience and nanotechnology have brought a great revolution in different areas. In particular, the synthesis of transition metal nanoparticles has been of great relevance for their use in areas such as biomedicine, antimicrobial properties or catalytic applications for chemical synthesis. Recently, an innovative straightforward and very efficient synthesis of these nanoparticles by simply using enzymes as inductors in aqueous media has been described. This represents a very green alternative to the different methodologies described in the literature for metal nanoparticles preparation where harsh conditions are necessary. In this review the most recent advances in the synthesis of metal nanoparticles by this green technology, explaining the synthetic mechanism, the role of the enzyme in the formation of the nanoparticles and the effect on the final properties of these nanoparticles, are summarised. The application of these novel metal nanoparticles-enzyme hybrids in synthetic chemistry as heterogeneous catalysts with metal or dual (enzymatic and metallic) activity and their capacity as environmental and antimicrobial agents have also been discussed.
近年来，纳米科学和纳米技术在不同领域带来了巨大变革。特别是，过渡金属纳米粒子的合成因其在生物医学、抗菌性能或化学合成催化应用等领域的用途而具有重大意义。最近，已经报道了一种创新的、直接且非常高效的合成这些纳米粒子的方法，即在水介质中简单地使用酶作为诱导剂。对于文献中描述的制备金属纳米粒子所需苛刻条件的不同方法而言，这是一种非常绿色的替代方法。在这篇综述中，总结了通过这种绿色技术合成金属纳米粒子的最新进展，解释了合成机理、酶在纳米粒子形成中的作用以及对这些纳米粒子最终性质的影响。还讨论了这些新型金属纳米粒子 - 酶杂化物在合成化学中作为具有金属或双重（酶促和金属）活性的多相催化剂的应用及其作为环境和抗菌剂的能力。
