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布基纳法索农村学龄前儿童的短期体重增加:一项随机对照试验的二次分析。

Short-term weight gain among preschool children in rural Burkina Faso: a secondary analysis of a randomised controlled trial.

机构信息

Francis I Proctor Foundation, University of California, San Francisco, California, USA.

Centre de Recherche en Sante de Nouna, Nouna, Burkina Faso.

出版信息

BMJ Open. 2019 Jul 29;9(7):e029634. doi: 10.1136/bmjopen-2019-029634.

Abstract

OBJECTIVES

Nutrition has profound effects on children's health outcomes and is linked to weight gain and cognitive development. We used data from a randomised controlled trial to evaluate the prospective associations between dietary, socioeconomic and demographic factors and short-term weight gain during the lean season in a rural area of Burkina Faso.

DESIGN

Prospective cohort data arising from a randomised controlled trial of the effect of antibiotic distribution on child growth and intestinal microbial diversity.

SETTING

Two rural communities in Nouna District, Burkina Faso.

PARTICIPANTS

246 children aged 6-59 months living in the study communities were enrolled in the study.

PRIMARY AND SECONDARY OUTCOME MEASURES

Anthropometric measurements, including weight and height, were obtained at baseline and 1 month.

RESULTS

Of 246 children, the median weight for wasted children at baseline (weight-for-height z-score <-2) was 9.7 kg (IQR 8.65-10.8) and the weight of non-wasted children was 12.8 kg (IQR 10.9-14.75). Food insecurity was significantly associated with decreased weight gain velocity (mean difference -0.03 g/kg/day, 95% CI -0.06 to -0.006, p=0.04).

CONCLUSION

Experiences of household food insecurity before the beginning of the lean season were associated with decreased weight gain in children in rural Burkina Faso during the lean season, although the mean difference was small. Understanding the relationship between timing of food insecurity and anthropometric outcomes may help to develop policies and health programme that address both of these issues.

TRIAL REGISTRATION NUMBER

NCT03187834.

摘要

目的

营养对儿童健康结果有深远影响,与体重增加和认知发展有关。我们使用来自一项随机对照试验的数据,评估了在布基纳法索农村地区的瘦季期间,饮食、社会经济和人口统计学因素与短期体重增加之间的前瞻性关联。

设计

这是一项评估抗生素分配对儿童生长和肠道微生物多样性影响的随机对照试验的前瞻性队列数据。

地点

布基纳法索努纳区的两个农村社区。

参与者

246 名年龄在 6-59 个月之间、居住在研究社区的儿童参加了这项研究。

主要和次要结果测量

在基线和 1 个月时进行了包括体重和身高在内的人体测量测量。

结果

在 246 名儿童中,基线时消瘦儿童(体重身高 z 分数 <-2)的中位数体重为 9.7 公斤(IQR 8.65-10.8),而非消瘦儿童的体重为 12.8 公斤(IQR 10.9-14.75)。粮食不安全与体重增加速度降低显著相关(平均差异 -0.03 g/kg/天,95%CI -0.06 至 -0.006,p=0.04)。

结论

在瘦季开始前经历家庭粮食不安全的情况与布基纳法索农村地区儿童在瘦季期间体重增加减少有关,尽管平均差异很小。了解粮食不安全发生时间与人体测量结果之间的关系,可能有助于制定同时解决这两个问题的政策和卫生方案。

试验注册

NCT03187834。

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