Kara Mustafa, Okur Aylin, Serin Halil İbrahim
1Bozok University, School of Medicine, Department of Obstetrics and Gynecology, Yozgat, Turkey; 2Eryaman Hastanesi, Department of Radiology, Ankara, Turkey; 3Bozok University, School of Medicine, Department of Radiology, Yozgat, Turkey.
Acta Clin Croat. 2019 Mar;58(1):103-106. doi: 10.20471/acc.2019.58.01.13.
The aim of the study was to investigate knee cartilage thickness in polycystic ovary syndrome (PCOS) patients using ultrasonography and to assess the effects of sex steroids on osteoarthritis development. A total of 90 female patients were enrolled in the study, including 47 patients diagnosed with PCOS as study group and 43 patients admitted to our hospital for any other complaints as control group. Ultrasonographic evaluation of both knees was performed in all patients. The knee cartilage thickness was measured at lateral condyle, intercondylar area and medial condyle. The measurements were averaged for each region. The mean femoral cartilage thickness was greater in the study group compared with control group in all regions, with a statistically significant difference (p<0.005). In conclusion, we found PCOS patients to have greater mean cartilage thickness, supporting the possible effects of sex steroids on osteoarthritis development.
本研究旨在利用超声检查多囊卵巢综合征（PCOS）患者的膝关节软骨厚度，并评估性类固醇对骨关节炎发展的影响。共有90名女性患者纳入本研究，其中47名被诊断为PCOS的患者作为研究组，43名因其他任何主诉入院的患者作为对照组。对所有患者的双膝进行超声评估。在外侧髁、髁间区和内侧髁测量膝关节软骨厚度。对每个区域的测量值求平均值。研究组在所有区域的平均股骨软骨厚度均大于对照组，差异有统计学意义（p<0.005）。总之，我们发现PCOS患者的平均软骨厚度更大，这支持了性类固醇对骨关节炎发展可能产生的影响。
