Barberán J
José Barberán, Servicio de Medicina Interna y Enfermedades infecciosas, Hospital Universitario HM Montepríncipe, Universidad San Pablo CEU. Madrid, Spain.
Rev Esp Quimioter. 2019 Sep;32 Suppl 3(Suppl 3):29-33.
Ceftobiprole is a fifth-generation cephalosporin approved for the treatment of adult community-acquired pneumonia and non-ventilator associated hospital-acquired pneumonia. However, its microbiological and pharmacokinetic profile is very attractive as armamentarium for empirical monotherapy treatment in other infections too. Among these, the following scenarios could be considered complicated skin and soft tissue infections, moderate-severe diabetic foot infections without bone involvement, vascular-catheter-associated-bloodstream infections, and fever without apparent focus in the hospitalized patient without septic shock or profound immunosuppression.
头孢比普是一种获批用于治疗成人社区获得性肺炎和非呼吸机相关性医院获得性肺炎的第五代头孢菌素。然而，其微生物学和药代动力学特性作为其他感染经验性单药治疗的武器库也非常有吸引力。其中，以下情况可考虑为复杂性皮肤和软组织感染、无骨受累的中重度糖尿病足感染、血管导管相关血流感染，以及在无感染性休克或严重免疫抑制的住院患者中无明显感染灶的发热。
