2009 - 2015年莫桑比克发热患者血清中寨卡病毒IgM抗体的回顾性调查
Retrospective investigation of IgM antibodies against Zika virus in serum from febrile patients in Mozambique, 2009-2015.
作者信息
Chelene Imelda Rogério, Ali Sadia, Mula Flora Inalda, Muianga Argentina Felisbela, Monteiro Vanessa Onofre, Oludele John, Chongo Inocêncio Salvador, José Américo, Amade Nádia Alves, António Virgílio Santo, Gudo Eduardo Samo
机构信息
Instituto Nacional de Saúde, Vila de Marracuene, EN1, Parcela nº3943, Maputo, Mozambique.
Centro de Colaboração em Saúde, Rua Damião de Gois, Maputo, Mozambique.
出版信息
BMC Res Notes. 2019 Jul 31;12(1):469. doi: 10.1186/s13104-019-4511-x.
OBJECTIVE
Zika virus (ZIKV) has emerged as an important health problem worldwide. The aim of this study was to investigate the occurrence, geographical distribution and trend of immunoglobulin M (IgM) antibodies against ZIKV between 2009 and 2015 in Mozambique.
RESULTS
The median age of participants was 3 years [interquartile range (IQR): 1.0-6.0 years)] and 56.5% (480/850) of them were male. Of the 850 samples, 42 (4.9%) were positive for IgM antibodies against ZIKV. Positive samples were found in 9 provinces of the country. Frequency of IgM antibodies against ZIKV was slightly higher in patients aged 5-9 years old, and in the north region of the country.
目的
寨卡病毒（ZIKV）已成为全球重要的健康问题。本研究旨在调查2009年至2015年莫桑比克针对ZIKV的免疫球蛋白M（IgM）抗体的发生情况、地理分布和趋势。
结果
参与者的中位年龄为3岁[四分位间距（IQR）：1.0 - 6.0岁]，其中56.5%（480/850）为男性。在850份样本中，42份（4.9%）针对ZIKV的IgM抗体呈阳性。在该国9个省份发现了阳性样本。5至9岁患者以及该国北部地区针对ZIKV的IgM抗体频率略高。
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