Calvo-Ortega Juan-Francisco, Moragues-Femenía Sandra, Laosa-Bello Coral, San José-Maderuelo Sol, Casals-Farran Joan
Servicio de Oncología Radioterápica, Hospital Quirónsalud, Barcelona, Spain.
Servicio de Oncología Radioterápica, Hospital Universitari Dexeus, Barcelona, Spain.
Rep Pract Oncol Radiother. 2019 Sep-Oct;24(5):421-427. doi: 10.1016/j.rpor.2019.07.003. Epub 2019 Jul 18.
To investigate whether the target-isocenter deviations reported by a conventional Winston-Lutz (WL) test actually reflect the shifts of the measured prescription isodose line with respect to the target.
A conventional WL test uses a metallic ball as a target that aims at several fields. But this test does not report information on the accuracy of the delivery in terms of dose.
A conventional WL test using a metallic pointer as a target (Pointer-WL test) has been recreated in the Eclipse treatment planning system over an acrylic phantom containing a radiochromic film (Dose-WL test). After Dose-WL test delivery, the shift of the 80% prescription isodose line with respect to the target center (d80%-center) was measured using film dosimetry. The Pointer-WL and Dose-WL tests were performed in 10 different sessions. The isocenter deviation reported by the Pointer-WL test was compared to the d80%-center vector, according to the three patient's directions (Left-Right or LR; Anterior-Posterior or AP; and Superior-Inferior or SI).
The deviations (mean ± SD) found for the Dose-WL tests (LR: 0.5 ± 0.4 mm; AP: 0.5 ± 0.4 mm; SI: 0.6 ± 0.2 mm) were in most cases less than 1 mm, and they were significantly smaller (all < 0.05) than the maximum deviations reported by the Pointer-WL tests (LR: 1.3 ± 0.3 mm; AP: 1.2 ± 0.4 mm; SI: 1.1 ± 0.3 mm).
The Dose-WL test described in this study allows estimating the spatial accuracy of the prescription isodose line.
研究传统温斯顿-卢茨(WL)测试报告的靶区等中心偏差是否实际反映了测量的处方等剂量线相对于靶区的位移。
传统的WL测试使用金属球作为靶区,针对多个射野。但该测试未报告剂量方面的输送准确性信息。
在包含放射变色胶片的丙烯酸体模上,于Eclipse治疗计划系统中重新创建了以金属指针作为靶区的传统WL测试(指针-WL测试)(剂量-WL测试)。剂量-WL测试输送后,使用胶片剂量测定法测量80%处方等剂量线相对于靶区中心的位移(d80%-中心)。指针-WL测试和剂量-WL测试在10个不同时段进行。根据三个患者方向(左右或LR;前后或AP;上下或SI),将指针-WL测试报告的等中心偏差与d80%-中心向量进行比较。
剂量-WL测试发现的偏差(平均值±标准差)(LR:0.5±0.4毫米;AP:0.5±0.4毫米;SI:0.6±0.2毫米)在大多数情况下小于1毫米,且显著小于指针-WL测试报告的最大偏差(LR:1.3±0.3毫米;AP:1.2±0.4毫米;SI:1.1±0.3毫米)(均<0.05)。
本研究中描述的剂量-WL测试能够估计处方等剂量线的空间准确性。