Poly(ionic liquid)s as a distinct receptor material to create a highly-integrated sensing platform for efficiently identifying numerous saccharides.

Saccharides have strong hydrophilicities, and are complex molecular structures with subtle structure differences, and tremendous structural variations. The creation of one sensing platform capable of efficiently identifying such target systems presents a huge challenge. Using the integration of unique multiple noncovalent interactions simultaneously occurring in poly(ionic liquid)s (PILs) with multiple signaling channels, in this research an aggregation-induced emission (AIE)-doped photonic structured PIL sphere is constructed. It is found that such a sphere can serve as a highly integrated platform to provide abundant fingerprints for directly sensing numerous saccharides with an unprecedented efficiency. As a demonstration, 23 saccharides can be conveniently identified using only one sphere. More importantly, by using simple ion-exchanges of PIL receptors or/and increasing the AIE signaling channels, this platform is able to perform, on demand, different sensing tasks very efficiently. This is demonstrated by using it for the detection of difficult targets, such as greatly extended saccharides as well as mixed targets, in real-life examples on one or two spheres. The findings show that this new class of platform is very promising for addressing the challenges of identifying saccharides.