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西班牙裔社区健康研究/拉丁裔研究中的得舒饮食与普遍存在的代谢综合征

DASH diet and prevalent metabolic syndrome in the Hispanic Community Health Study/Study of Latinos.

作者信息

Joyce Brian T, Wu Donghong, Hou Lifang, Dai Qi, Castaneda Sheila F, Gallo Linda C, Talavera Gregory A, Sotres-Alvarez Daniela, Van Horn Linda, Beasley Jeannette M, Khambaty Tasneem, Elfassy Tali, Zeng Donglin, Mattei Josiemer, Corsino Leonor, Daviglus Martha L

机构信息

Center for Population Epigenetics, Robert H. Lurie Comprehensive Cancer Center, Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 N. Lake Shore Dr., Suite 1400, Chicago, IL 60611, USA.

Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA.

出版信息

Prev Med Rep. 2019 Jul 16;15:100950. doi: 10.1016/j.pmedr.2019.100950. eCollection 2019 Sep.

Abstract

The Dietary Approaches to Stop Hypertension (DASH) diet is recommended for lowering blood pressure and preventing cardiovascular disease (CVD), but little data exist on these associations in US Hispanics/Latinos. We sought to assess associations between DASH score and prevalence of metabolic syndrome (MetS) and its components in diverse Hispanics/Latinos. We studied 10,741 adults aged 18-74 in the multicenter Hispanic Community Health Study/Study of Latinos. Dietary intake was measured using two 24-hour recalls, and MetS defined per the 2009 harmonized guidelines. We assessed cross-sectional associations of DASH score and MetS (and its dichotomized components) using survey logistic regression, and DASH and MetS continuous components using linear regression. We also stratified these models by Hispanic/Latino heritage group to explore heritage-specific associations. We found no associations between DASH and MetS prevalence. DASH was inversely associated with both measures of blood pressure (p < 0.01 for systolic and p < 0.001 for diastolic) in the overall cohort. DASH was also inversely associated with diastolic blood pressure in the Mexican (p < 0.05), Central American (p < 0.05), and South American (p < 0.01) groups; triglycerides (p < 0.05) in the Central American group; fasting glucose overall (p < 0.01) and in the Mexican group (p < 0.01); and waist circumference overall (p < 0.05) and in the South American group (p < 0.01). DASH was positively associated with HDL-cholesterol (p < 0.01) in the Central American group. DASH may better capture diet-MetS associations in Hispanic/Latino subpopulations such as Central/South Americans; this study also adds evidence that Hispanics/Latinos should be analyzed by heritage. Further research, and/or culturally tailored DASH measures will help further explain between-heritage differences.

摘要

“终止高血压膳食疗法(DASH)饮食”被推荐用于降低血压和预防心血管疾病(CVD),但在美国西班牙裔/拉丁裔人群中,关于这些关联的数据很少。我们试图评估DASH评分与不同西班牙裔/拉丁裔人群中代谢综合征(MetS)及其组分患病率之间的关联。我们在多中心西班牙裔社区健康研究/拉丁裔研究中,对10741名18 - 74岁的成年人进行了研究。通过两次24小时饮食回顾来测量饮食摄入量,并根据2009年统一指南定义代谢综合征。我们使用调查逻辑回归评估DASH评分与代谢综合征(及其二分法组分)的横断面关联,使用线性回归评估DASH与代谢综合征连续组分的关联。我们还按西班牙裔/拉丁裔血统组对这些模型进行分层,以探索特定血统的关联。我们发现DASH与代谢综合征患病率之间没有关联。在整个队列中,DASH与两种血压测量值均呈负相关(收缩压p < 0.01,舒张压p < 0.001)。DASH在墨西哥裔(p < 0.05)、中美洲裔(p < 0.05)和南美洲裔(p < 0.01)组中也与舒张压呈负相关;在中美洲裔组中与甘油三酯呈负相关(p < 0.05);在总体人群中(p < 0.01)以及墨西哥裔组中(p < 0.01)与空腹血糖呈负相关;在总体人群中(p < 0.05)以及南美洲裔组中(p < 0.01)与腰围呈负相关。在中美洲裔组中,DASH与高密度脂蛋白胆固醇呈正相关(p < 0.01)。DASH可能能更好地捕捉西班牙裔/拉丁裔亚人群(如中美洲/南美洲人群)中饮食与代谢综合征的关联;这项研究还补充了证据,表明应该按血统对西班牙裔/拉丁裔人群进行分析。进一步的研究和/或针对不同文化背景定制的DASH措施将有助于进一步解释不同血统之间的差异。

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