• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The increase of mTOR expression is consistent with FoxO1 decrease at gene level in acne but not in psoriasis.

作者信息

Lembo Serena, Di Caprio Roberta, Balato Anna, Caiazzo Giuseppina, Fabbrocini Gabriella, Skroza Nevena, Tolino Ersilia, Potenza Concetta

机构信息

Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Salerno, Italy.

Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.

出版信息

Arch Dermatol Res. 2020 Jan;312(1):77-80. doi: 10.1007/s00403-019-01959-0. Epub 2019 Jul 31.

DOI:10.1007/s00403-019-01959-0
PMID:31367853
Abstract
摘要

相似文献

1
The increase of mTOR expression is consistent with FoxO1 decrease at gene level in acne but not in psoriasis.在痤疮中，mTOR表达的增加与基因水平上FoxO1的减少相一致，但在银屑病中并非如此。
Arch Dermatol Res. 2020 Jan;312(1):77-80. doi: 10.1007/s00403-019-01959-0. Epub 2019 Jul 31.
2
Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin-like growth factor-1 in patients with acne vulgaris and their relationship with diet.痤疮患者皮肤中雷帕霉素靶蛋白和叉头框转录因子 O1 的表达及其与血清胰岛素样生长因子-1 的关系与饮食的关系。
Br J Dermatol. 2016 Jun;174(6):1299-307. doi: 10.1111/bjd.14409. Epub 2016 Apr 20.
3
Dysregulation of FOXO1 (Forkhead Box O1 Protein) Drives Calcification in Arterial Calcification due to Deficiency of CD73 and Is Present in Peripheral Artery Disease.FOXO1（叉头框蛋白 O1 蛋白）失调导致 CD73 缺乏引起的动脉钙化中的钙化，并存在于外周动脉疾病中。
Arterioscler Thromb Vasc Biol. 2020 Jul;40(7):1680-1694. doi: 10.1161/ATVBAHA.119.313765. Epub 2020 May 7.
4
Mechanistic target of rapamycin (mTOR) expression is increased in acne patients' skin.雷帕霉素作用靶点（mTOR）在痤疮患者皮肤中的表达增加。
Exp Dermatol. 2016 Feb;25(2):153-5. doi: 10.1111/exd.12885. Epub 2015 Dec 3.
5
Effect of oral isotretinoin on the nucleo-cytoplasmic distribution of FoxO1 and FoxO3 proteins in sebaceous glands of patients with acne vulgaris.口服异维 A 酸对寻常痤疮患者皮脂腺中 FoxO1 和 FoxO3 蛋白核质分布的影响。
Exp Dermatol. 2018 Dec;27(12):1344-1351. doi: 10.1111/exd.13787. Epub 2018 Oct 17.
6
Does Resveratrol Improve Insulin Signalling in HepG2 Cells?白藜芦醇是否能改善 HepG2 细胞的胰岛素信号传导？
Can J Diabetes. 2017 Apr;41(2):211-216. doi: 10.1016/j.jcjd.2016.09.015. Epub 2016 Dec 23.
7
Potential role of FoxO1 and mTORC1 in the pathogenesis of Western diet-induced acne.FoxO1 和 mTORC1 在西方饮食诱导型痤疮发病机制中的潜在作用。
Exp Dermatol. 2013 May;22(5):311-5. doi: 10.1111/exd.12142.
8
FoxO1 enhances differentiation and apoptosis in human primary keratinocytes.FoxO1 增强人原代角质形成细胞的分化和凋亡。
Exp Dermatol. 2018 Nov;27(11):1254-1260. doi: 10.1111/exd.13775. Epub 2018 Sep 26.
9
Novel Insights for Multiple Sclerosis and Demyelinating Disorders with Apoptosis, Autophagy, FoxO, and mTOR.关于多发性硬化症和脱髓鞘疾病与细胞凋亡、自噬、FoxO和mTOR的新见解
Curr Neurovasc Res. 2021;18(2):169-171. doi: 10.2174/1567202618999210505124235.
10
Regulation of glucose uptake and inflammation markers by FOXO1 and FOXO3 in skeletal muscle.FOXO1 和 FOXO3 在骨骼肌中对葡萄糖摄取和炎症标志物的调节作用。
Mol Metab. 2019 Feb;20:79-88. doi: 10.1016/j.molmet.2018.09.011. Epub 2018 Nov 16.

引用本文的文献

1
Transcriptomic Analyses Predict Enhanced Metabolic Activity and Therapeutic Potential of mTOR Inhibitors in Acne-Prone Skin.转录组学分析预测mTOR抑制剂在易长痤疮皮肤中的代谢活性增强及治疗潜力
JID Innov. 2024 Sep 7;4(6):100306. doi: 10.1016/j.xjidi.2024.100306. eCollection 2024 Nov.
2
A Study of FoxO1, mTOR, miR-21, miR-29b, and miR-98 Expression Levels Regarding Metabolic Syndrome in Acne Vulgaris Patients.寻常痤疮患者中与代谢综合征相关的FoxO1、mTOR、miR-21、miR-29b和miR-98表达水平的研究
Cureus. 2024 Mar 20;16(3):e56562. doi: 10.7759/cureus.56562. eCollection 2024 Mar.
3
Acne Transcriptomics: Fundamentals of Acne Pathogenesis and Isotretinoin Treatment.
痤疮转录组学：痤疮发病机制和异维 A 酸治疗的基础。
Cells. 2023 Nov 10;12(22):2600. doi: 10.3390/cells12222600.
4
Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation.水杨梅黄酮通过双重靶向 mTOR/IL-17A 和自噬来缓解银屑病样皮肤炎症。
Front Immunol. 2023 Jan 18;13:1075804. doi: 10.3389/fimmu.2022.1075804. eCollection 2022.
5
Insulin Resistance and Acne: The Role of Metformin as Alternative Therapy in Men.胰岛素抵抗与痤疮：二甲双胍作为男性替代疗法的作用。
Pharmaceuticals (Basel). 2022 Dec 26;16(1):27. doi: 10.3390/ph16010027.
6
Isotretinoin treatment upregulates the expression of p53 in the skin and sebaceous glands of patients with acne vulgaris.异维 A 酸治疗可上调寻常痤疮患者皮肤和皮脂腺中 p53 的表达。
Arch Dermatol Res. 2023 Jul;315(5):1355-1365. doi: 10.1007/s00403-022-02508-y. Epub 2022 Dec 31.
7
Lifetime Impact of Cow's Milk on Overactivation of mTORC1: From Fetal to Childhood Overgrowth, Acne, Diabetes, Cancers, and Neurodegeneration.牛奶对 mTORC1 过度激活的终生影响：从胎儿到儿童期过度生长、痤疮、糖尿病、癌症和神经退行性变。
Biomolecules. 2021 Mar 9;11(3):404. doi: 10.3390/biom11030404.
8
18β-Glycyrrhetinic acid induces human HaCaT keratinocytes apoptosis through ROS-mediated PI3K-Akt signaling pathway and ameliorates IMQ-induced psoriasis-like skin lesions in mice.18β-甘草次酸通过 ROS 介导的 PI3K-Akt 信号通路诱导人 HaCaT 角质形成细胞凋亡，并改善咪喹莫特诱导的小鼠银屑病样皮肤损伤。
BMC Pharmacol Toxicol. 2020 Jun 3;21(1):41. doi: 10.1186/s40360-020-00419-0.
9
Exploring Anti-Fungal, Anti-Microbial and Anti-Inflammatory Properties of a Topical Non-Steroidal Barrier Cream in Face and Chest Seborrheic Dermatitis.探索一种局部用非甾体屏障乳膏对面部和胸部脂溢性皮炎的抗真菌、抗菌和抗炎特性。
Dermatol Ther (Heidelb). 2020 Feb;10(1):87-98. doi: 10.1007/s13555-019-00339-w. Epub 2019 Nov 8.