Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
Department of Gastroenterology, Hepatology, and Nutrition, University of Texas MD Anderson Cancer Center, Houston, Texas.
J Surg Oncol. 2019 Oct;120(5):858-863. doi: 10.1002/jso.25648. Epub 2019 Jul 31.
Currently, colorectal cancers accounted for the second-highest number of cancer deaths in the US. Hereditary syndromes, strong family history, and inflammatory bowel disease are all conditions that confer predisposition risks. In hereditary syndromes, screening must be more frequent and start earlier. With familial risk, screening should depend on the age of cancer onset and number of affected relatives. For inflammatory bowel disease, surveillance should depend on duration, severity, and extent of colitis.
目前，结直肠癌是美国癌症死亡人数第二高的癌症。遗传性综合征、强烈的家族史和炎症性肠病都是易患风险的情况。在遗传性综合征中，筛查必须更加频繁且更早开始。对于家族性风险，筛查应取决于癌症发病年龄和受影响亲属的数量。对于炎症性肠病，监测应取决于结肠炎的持续时间、严重程度和范围。
