College of Pharmacy, Jazan University, Jazan, Kingdom of Saudi Arabia.
Ethnopharmacology Research Unit, Jazan University, Jazan, Kingdom of Saudi Arabia.
Nat Prod Res. 2021 Apr;35(8):1379-1383. doi: 10.1080/14786419.2019.1645659. Epub 2019 Aug 1.
The purpose of this study was to investigate the chemical composition and anti-bacterial properties of the bioactive principles of (Turner) C.Agardh, a brown seaweed in Red sea of Jazan province, Kingdom of Saudi Arabia. Crystals were obtained from the petroleum ether extract of and subjected to chemical tests, FTIR spectroscopic analysis and NMR analysis to identify their chemical composition, and to study their antibacterial properties against selected human pathogenic bacteria. In addition, GC-MS analysis was performed to identify the bioactive compounds in the crude petroleum ether extract. Results of the antibacterial effect of the crystal analyte showed a wide spectrum of activity against the screened human pathogenic bacteria.
本研究旨在探究沙特阿拉伯吉赞省红海的褐藻（Turner）C.Agardh 的生物活性成分的化学组成和抗菌特性。从该海藻的石油醚提取物中获得晶体，并进行化学测试、傅里叶变换红外光谱分析和核磁共振分析，以确定其化学组成，并研究其对选定的人类病原菌的抗菌特性。此外，还进行了 GC-MS 分析以鉴定粗石油醚提取物中的生物活性化合物。晶体分析物的抗菌效果结果表明，其对筛选出的人类病原菌具有广谱活性。
