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褐藻属的药理和天然产物多样性

Pharmacological and natural products diversity of the brown algae genus .

作者信息

Rushdi Mohammed I, Abdel-Rahman Iman A M, Saber Hani, Attia Eman Zekry, Abdelraheem Wedad M, Madkour Hashem A, Hassan Hossam M, Elmaidomy Abeer H, Abdelmohsen Usama Ramadan

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, South Valley University 83523 Qena Egypt.

Department of Botany and Microbiology, Faculty of Science, South Valley University 83523 Qena Egypt.

出版信息

RSC Adv. 2020 Jul 1;10(42):24951-24972. doi: 10.1039/d0ra03576a. eCollection 2020 Jun 29.

DOI:10.1039/d0ra03576a
PMID:35517468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9055232/
Abstract

(F. Sargassaceae) is an important seaweed excessively distributed in tropical and subtropical regions. Different species of have folk applications in human nutrition and are considered a rich source of vitamins, carotenoids, proteins, and minerals. Many bioactive compounds chemically classified as terpenoids, sterols, sulfated polysaccharides, polyphenols, sargaquinoic acids, sargachromenol, and pheophytin were isolated from different species. These isolated compounds and/or extracts exhibit diverse biological activities, including analgesic, anti-inflammatory, antioxidant, neuroprotective, anti-microbial, anti-tumor, fibrinolytic, immune-modulatory, anti-coagulant, hepatoprotective, and anti-viral activities. This review covers the literature from 1974 to 2020 on the genus , and reveal the active components together with their biological activities according to their structure to create a base for additional studies on the clinical applications of .

摘要

(马尾藻科)是一种重要的海藻,广泛分布于热带和亚热带地区。不同种类的马尾藻在人类营养方面有民间应用,被认为是维生素、类胡萝卜素、蛋白质和矿物质的丰富来源。从不同种类的马尾藻中分离出了许多化学分类为萜类、甾醇、硫酸化多糖、多酚、马尾藻醌酸、马尾藻色烯醇和脱镁叶绿素的生物活性化合物。这些分离出的化合物和/或提取物表现出多种生物活性,包括镇痛、抗炎、抗氧化、神经保护、抗菌、抗肿瘤、纤维蛋白溶解、免疫调节、抗凝血、肝脏保护和抗病毒活性。本综述涵盖了1974年至2020年关于马尾藻属的文献,并根据其结构揭示了活性成分及其生物活性,为马尾藻临床应用的进一步研究奠定基础。

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