Identification of long noncoding RNA RP11-169F17.1 and RP11-669N7.2 as novel prognostic biomarkers of stomach adenocarcinoma based on integrated bioinformatics analysis.

We aim to identify differentially expressed long noncoding RNAs (lncRNAs) and explored their functional roles in stomach adenocarcinoma. Based on public omics data, we identified disregulated lncRNAs and investigated their prognostic values and potential functions based on ceRNA hypothesis. Among the 52 differentially expressed lncRNAs, upregulated and were significantly associated with both poor overall survival and disease-free survival. and strongly correlated with microRNAs in cancer, cell proliferation and differentiation. and closely related to infection-induced gastritis, duodenal ulcer, gastric cancer and mucosa-associated lymphoid tissue lymphoma. and act as novel prognostic biomarkers of stomach adenocarcinoma and may also play an important role in infection-induced gastric diseases.