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法国老年护理机构 80 岁以上个体心力衰竭管理的全国性调查。

National survey on the management of heart failure in individuals over 80 years of age in French geriatric care units.

机构信息

Assistance Publique des Hopitaux de Paris, Hopital Broca, 54-56 rue Pascal, 75013, Paris, France.

Sorbonne Paris-Cité, Université Paris-Descartes, Equipe d'Accueil 4468, Paris, France.

出版信息

BMC Geriatr. 2019 Aug 1;19(1):204. doi: 10.1186/s12877-019-1215-y.

Abstract

BACKGROUND

To evaluate the prevalence and management of heart failure (HF) in very old patients in geriatric settings.

METHODS

Members of the French Society of Geriatrics and Gerontology throughout France were invited to participate in a point prevalence survey and to include all patients ≥80 years old, hospitalized in geriatric settings, with HF (stable or decompensated) on June 18, 2012. General characteristics, presence of comorbidities, blood tests and medications were recorded.

RESULTS

Among 7,197 patients in geriatric institution, prevalence of HF was 20.5% (n = 1,478): (27% in acute care, 24.2% in rehabilitation care and 18% in nursing home). Mean age was 88.2 (SD = 5.2) and Charlson co morbidity score was high (8.49 (SD = 2.21)). Left ventricular ejection fraction (LVEF) was available in 770 (52%) patients: 536 (69.6%) had a preserved LVEF (≥ 50%), 120 (15.6%) a reduced LVEF (< 40%), and 114 (14.8%) a midrange LVEF (40-49%). Prescription of recommended HF drugs was low: 42.6% (629) used Angiotensin Converting Enzyme Inhibitors (ACEI) or Angiotensin Receptor Blockers (ARBs), 48.0% (709) β-blockers, and 21.9% (324) ACEI or ARB with β-blockers, even in reduced LVEF. In multivariate analysis ACEI or ARBs were more often used in patients with myocardial infarction (1.36 (1.04-1.78)), stroke (1.42 (1.06-1.91)), and diabetes (1.54 (1.14-2.06)). β blockers were more likely used in patients with myocardial infarction (2.06 (1.54-2.76)) and atrial fibrillation (1.70 (1.28-2.28)).

CONCLUSION

In this large very old population, prevalence of HF was high. Recommended HF drugs were underused even in reduced LVEF. These results indicate that management of HF in geriatric settings can still be improved.

摘要

背景

评估老年医学环境中非常高龄患者心力衰竭(HF)的患病率和管理情况。

方法

法国老年医学学会的成员被邀请参与一项时点患病率调查,并纳入所有 2012 年 6 月 18 日在老年医学环境中住院、患有 HF(稳定或失代偿)的年龄≥80 岁的患者。记录一般特征、合并症、血液检查和药物治疗情况。

结果

在 7197 名入住老年机构的患者中,HF 的患病率为 20.5%(n=1478):(急性护理 27%、康复护理 24.2%和护理院 18%)。平均年龄为 88.2(SD=5.2),Charlson 合并症评分较高(8.49(SD=2.21))。左心室射血分数(LVEF)可用于 770 名(52%)患者:536 名(69.6%)具有保留的 LVEF(≥50%),120 名(15.6%)具有降低的 LVEF(<40%),114 名(14.8%)具有中等范围的 LVEF(40-49%)。推荐的 HF 药物处方率较低:42.6%(629 名)使用血管紧张素转换酶抑制剂(ACEI)或血管紧张素受体阻滞剂(ARB),48.0%(709 名)使用β受体阻滞剂,21.9%(324 名)使用 ACEI 或 ARB 加β受体阻滞剂,即使在 LVEF 降低的情况下也是如此。多变量分析显示,ACEI 或 ARB 更常用于心肌梗死(1.36(1.04-1.78))、中风(1.42(1.06-1.91))和糖尿病(1.54(1.14-2.06))患者。β受体阻滞剂更可能用于心肌梗死(2.06(1.54-2.76))和心房颤动(1.70(1.28-2.28))患者。

结论

在这个庞大的非常高龄人群中,HF 的患病率很高。即使在 LVEF 降低的情况下,也很少使用推荐的 HF 药物。这些结果表明,老年医学环境中 HF 的管理仍有待改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fae8/6670218/8977f2ae6bed/12877_2019_1215_Fig1_HTML.jpg

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