Bostanci Asli, Ozbudak Irem Hicran, Turhan Murat
1Department of Otolaryngology, Head and Neck Surgery, Akdeniz University School of Medicine, Dumlupinar Boulevard, H-Blok, 07058 Konyaalti, Antalya, Turkey.
2Department of Pathology, Akdeniz University School of Medicine, Antalya, Turkey.
J Maxillofac Oral Surg. 2019 Sep;18(3):391-394. doi: 10.1007/s12663-018-1163-7. Epub 2018 Oct 9.
Hyalinizing clear cell carcinoma (HCCC) is a rare low-grade salivary gland tumor with distinctive clear cell morphology, accounting for < 1% of all salivary gland tumors. In the majority of cases, the tumor originates typically from the minor salivary glands in the oral cavity. A total of 155 cases of HCCCs from head and neck region have been reported in the literature until 2017, of which only 16 are of maxillary origin. Due to its low incidence, there is no clear consensus on prognostic factors and optimal treatment strategies yet. In this paper, a new case of HCCC of the maxilla is presented and its clinical and histopathological features are discussed.
透明细胞癌(HCCC)是一种罕见的低级别涎腺肿瘤,具有独特的透明细胞形态,占所有涎腺肿瘤的比例小于1%。在大多数情况下,肿瘤通常起源于口腔中的小涎腺。截至2017年,文献中总共报道了155例头颈部区域的透明细胞癌,其中只有16例起源于上颌骨。由于其发病率低,关于预后因素和最佳治疗策略尚无明确共识。本文报告了一例上颌骨透明细胞癌的新病例,并讨论了其临床和组织病理学特征。