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《鼻咽癌诊断与治疗中国专家共识:基于当前实践的证据及未来展望》

Chinese expert consensus on diagnosis and treatment of nasopharyngeal carcinoma: evidence from current practice and future perspectives.

作者信息

Lang Jinyi, Hu Chaosu, Lu Taixiang, Pan Jianji, Lin Tongyu

机构信息

Department of Radiation Oncology, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.

Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.

出版信息

Cancer Manag Res. 2019 Jul 10;11:6365-6376. doi: 10.2147/CMAR.S197544. eCollection 2019.

DOI:10.2147/CMAR.S197544
PMID:31372041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6628961/
Abstract

Nasopharyngeal carcinoma (NPC) is a rare type of head and neck cancer, with a higher incidence reported only in Southeast Asia and Northern Africa. Owing to the rarity of NPC occurrence, no internationally accepted consensus or guideline for its diagnosis and treatment is available. Based on the current evidences and practices, the Chinese experts on multidisciplinary diagnosis and treatment of NPC were designated to develop a national consensus for the treatment strategy of NPC. In this consensus, we report the development for improving the treatment efficacy and quality of life of NPC patients in China. The consensus also describes and recommends the role of multidisciplinary management approach in the management of NPC. A multidisciplinary team should include experts from different domains who can cater to the individualized needs of patients with NPC in a much more efficient manner. In addition, the team may also play a key role in developing guiding principles for future research, contributing to the improvement in the management of NPC.

摘要

鼻咽癌(NPC)是一种罕见的头颈部癌症,仅在东南亚和北非地区有较高的发病率报告。由于鼻咽癌发病罕见,目前尚无国际公认的诊断和治疗共识或指南。基于当前的证据和实践,中国鼻咽癌多学科诊断与治疗专家被指定制定一项关于鼻咽癌治疗策略的全国性共识。在本共识中,我们报告了为提高中国鼻咽癌患者的治疗效果和生活质量所做的进展。该共识还描述并推荐了多学科管理方法在鼻咽癌管理中的作用。一个多学科团队应包括来自不同领域的专家,他们能够以更高效的方式满足鼻咽癌患者的个性化需求。此外,该团队在制定未来研究的指导原则方面也可能发挥关键作用,有助于改善鼻咽癌的管理。

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2
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Oncotarget. 2017 Oct 20;8(59):100764-100772. doi: 10.18632/oncotarget.21992. eCollection 2017 Nov 21.
3
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J Clin Oncol. 2017 Dec 20;35(36):4050-4056. doi: 10.1200/JCO.2017.73.3675. Epub 2017 Aug 24.
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