Yamashita Kaori, Horiuchi Toshihide, Hayashida Akihiro, Tachibana Hidekazu, Toki Daisuke, Kondo Tsunenori
Department of Urology, Tokyo Women's Medical University, Medical Center East, 2-1-10, Nishiogu, Arakawa-ku, Tokyo, 116-8567, Japan.
Urol Case Rep. 2019 Jul 17;26:100971. doi: 10.1016/j.eucr.2019.100971. eCollection 2019 Sep.
A case of multiple myeloma with testicular involvement is rare. We report a 72-year-old male with testicular infiltration as extramedullary disease of IgD λ-type multiple myeloma. The patient received systemic treatment, which included high orchiectomy, anticancer chemotherapy, and radiation therapy for bone metastasis. Eight months after the initial diagnosis, he remains alive. The testis is a rare location for extramedullary disease of multiple myeloma. Testicular involvement of multiple myeloma indicates a poor prognosis. The particular treatment strategy for extramedullary disease in multiple myeloma remains unclear. Testicular involvement of multiple myeloma is reviewed and discussed in this paper.
睾丸受累的多发性骨髓瘤病例罕见。我们报告一例72岁男性,其睾丸浸润为IgD λ型多发性骨髓瘤的髓外病变。患者接受了全身治疗,包括高位睾丸切除术、抗癌化疗以及针对骨转移的放射治疗。初始诊断八个月后,他仍然存活。睾丸是多发性骨髓瘤髓外病变的罕见部位。多发性骨髓瘤的睾丸受累提示预后不良。多发性骨髓瘤髓外病变的具体治疗策略仍不明确。本文对多发性骨髓瘤的睾丸受累进行了综述和讨论。