Levin D L, Roth D E, Muhlbauer J E
University of New York, Upstate Medical Center, Syracuse.
J Am Acad Dermatol. 1988 Aug;19(2 Pt 2):393-6. doi: 10.1016/s0190-9622(88)70185-1.
A case of dysplastic nevus syndrome in a 41-year-old tyrosinase-positive oculocutaneous albino man is presented. Clinically the patient exhibited multiple amelanotic lesions; histologic examination provided the diagnosis of dysplastic nevus syndrome. Fontana-Masson silver staining revealed the presence of melanin in the nevus cells. Hair bulbs incubated in tyrosine buffer produced melanin. This is the second reported case of dysplastic nevus syndrome in an oculocutaneous albino and the first case of dysplastic nevus syndrome in a tyrosinase-positive albino of which we are aware.
本文报告了一例41岁酪氨酸酶阳性的眼皮肤白化病男性的发育异常痣综合征病例。临床上，该患者表现出多个无色素性病变；组织学检查确诊为发育异常痣综合征。Fontana-Masson银染色显示痣细胞中有黑色素存在。在酪氨酸缓冲液中孵育的毛球产生了黑色素。这是第二例报道的眼皮肤白化病患者发生发育异常痣综合征的病例，也是我们所知的第一例酪氨酸酶阳性白化病患者发生发育异常痣综合征的病例。
