Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Division of Endocrinology, Diabetes, and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Endocrine. 2019 Oct;66(1):18-26. doi: 10.1007/s12020-019-02023-7. Epub 2019 Aug 1.
The purpose of this article will be to review the basics of thyroid hormone therapy, including various thyroid hormone formulations, the institution and monitoring of thyroid hormone therapy, adverse effects of overtreatment, the management of patients with persistent symptoms despite normal thyroid function tests, and potential new innovations in thyroid hormone therapy. The conclusions support the necessity to personalize thyroid hormone replacement therapy in hypothyroid patients.
本文旨在回顾甲状腺激素治疗的基础知识,包括各种甲状腺激素制剂、甲状腺激素治疗的开始和监测、过度治疗的不良反应、尽管甲状腺功能检查正常但仍有持续症状的患者的管理,以及甲状腺激素治疗的潜在新创新。这些结论支持对甲状腺功能减退症患者进行个体化甲状腺激素替代治疗的必要性。