National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, Bristol, UK.
Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Learning and Research Building (Level 1), Southmead Hospital, Bristol, BS10 5NB, UK.
Eur J Epidemiol. 2019 Oct;34(10):983-986. doi: 10.1007/s10654-019-00544-z. Epub 2019 Aug 1.
Emerging evidence suggests there is an inverse and independent association between sauna bathing and arterial thrombotic disease. However, the potential association between sauna bathing and venous thromboembolism (VTE) has not yet been investigated. We aimed to assess the prospective association between frequency of sauna bathing and the risk of VTE. Baseline sauna bathing habits were assessed in 2242 men aged 42-61 years without a history of VTE in the Kuopio Ischemic Heart Disease prospective cohort. Cox proportional hazards models were used to estimate hazard ratios (HRs) with 95% confidence intervals (CIs) for VTE. During a median follow-up of 24.9 years, 146 (6.5%) incident VTE events were recorded. In age-adjusted analyses, the HRs 95% (CIs) of VTE were 0.67 (0.47-0.96) and 0.95 (0.53-1.70) for participants who had 2-3 and ≥ 4 sauna sessions per week respectively compared with participants who had ≤ 1 sauna session per week. After further adjustment for several established risk factors including lifestyle factors, the corresponding HRs (95% CIs) were 0.67 (0.46-0.96) and 0.92 (0.51-1.68) respectively. Having sauna baths was associated with a reduced risk of VTE in a middle-aged male Caucasian population. Further studies in other populations and age groups are required to confirm these findings.
新出现的证据表明,洗桑拿浴与动脉血栓性疾病呈负相关且独立相关。然而,洗桑拿浴与静脉血栓栓塞症(VTE)之间的潜在关联尚未得到研究。我们旨在评估洗桑拿浴的频率与 VTE 风险之间的前瞻性关联。在库奥皮奥缺血性心脏病前瞻性队列中,对 2242 名年龄在 42-61 岁、无 VTE 病史的男性进行了基线桑拿浴习惯评估。使用 Cox 比例风险模型估计 VTE 的风险比(HR)及其 95%置信区间(CI)。在中位随访 24.9 年期间,记录了 146 例(6.5%)VTE 事件。在年龄调整分析中,每周洗 2-3 次和每周洗≥4 次桑拿浴的参与者发生 VTE 的 HR(95%CI)分别为 0.67(0.47-0.96)和 0.95(0.53-1.70),而每周洗≤1 次桑拿浴的参与者为 1.00。进一步调整了包括生活方式因素在内的几个既定危险因素后,相应的 HR(95%CI)分别为 0.67(0.46-0.96)和 0.92(0.51-1.68)。在中年白种男性人群中,洗桑拿浴与 VTE 风险降低相关。需要在其他人群和年龄组中进行进一步的研究来证实这些发现。