General Studies, Gateway Technical College, Kenosha, WI, 53144, USA.
The Key Laboratory of Aquatic Biodiversity and Conservation of the Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072, China.
Antonie Van Leeuwenhoek. 2019 Dec;112(12):1815-1826. doi: 10.1007/s10482-019-01303-6. Epub 2019 Aug 1.
Plesiomonas shigelloides is a Gram-negative rod-shaped bacterium which has been isolated from humans, animals and the environment. It has been associated with diarrhoeal disease in humans and various epizootic diseases in animals. In this study P. shigelloides strains were isolated from the faecal material of a captive Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis; YFP) living in semi-natural conditions in China. Plesiomonas shigelloides strain EE2 was subjected to whole genome sequencing. The draft genome was then compared to the genome sequences of ten other P. shigelloides isolates using the Pathosystems Resource Integration Center pipeline. In addition to several virulence factors which have been previously reported, we are proposing new candidate virulence factors such as a repeats-in-toxin protein, lysophospholipase, a twin-arginine translocation system and the type VI secretion effector Phospholipase A1.
类志贺邻单胞菌是一种革兰氏阴性杆状细菌，已从人类、动物和环境中分离出来。它与人类的腹泻病和动物的各种流行性病有关。在这项研究中，类志贺邻单胞菌菌株从生活在中国半自然条件下的一只圈养长江江豚（Neophocaena asiaeorientalis asiaeorientalis；YFP）的粪便材料中分离出来。类志贺邻单胞菌 EE2 菌株进行了全基因组测序。然后，使用 Pathosystems Resource Integration Center 管道将该基因组草案与其他 10 株类志贺邻单胞菌的基因组序列进行了比较。除了之前报道的几种毒力因子外，我们还提出了新的候选毒力因子，如重复毒素蛋白、溶血磷脂酶、双精氨酸转运系统和 VI 型分泌效应物磷脂酶 A1。
