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下颌前移矫治器治疗阻塞性睡眠呼吸暂停——一个警示故事。

Mandibular advancement splints for obstructive sleep apnoea - a cautionary tale.

机构信息

Oral and Maxillofacial Surgery Unit of South Australia, Adelaide, South Australia, Australia.

出版信息

Aust Dent J. 2019 Dec;64(4):359-364. doi: 10.1111/adj.12712. Epub 2019 Aug 28.

Abstract

BACKGROUND

Obstructive sleep apnoea is a serious medical condition of increasing prevalence that has a multitude of treatment modalities. The aim of this study was to review the results of patients treated with mandibular advancement splints in the Oral and Maxillofacial Surgery Unit of South Australia to inform ongoing practice in this area.

METHODS

The casenotes of patients who received a splint for obstructive sleep apnoea between January 2008 and June 2014 were audited. Data collection included referral and demographic details, sleep study results, splint type and follow-up details.

RESULTS

Three hundred and four patients were identified as having been provided a mandibular advancement splint for obstructive sleep apnoea, of which 82 had diagnostic and splint-in-situ sleep studies available for comparison. It was observed that 27 had clinically significant objective improvement, 40 had no clinically significant change and 15 had clinically worse OSA following MAS therapy. Mean reductions in Apnoea-Hypopnoea Index and Respiratory Disturbance Index were eight events (27%) and 13 events (33%) per hour respectively with treatment.

CONCLUSIONS

Based on this study, mandibular advancement splint therapy is a viable treatment for a subset of patients with obstructive sleep apnoea. Protocol driven, multi-disciplinary care with auditing of results is recommended.

摘要

背景

阻塞性睡眠呼吸暂停是一种日益普遍的严重医学病症,有多种治疗方法。本研究旨在回顾在南澳大利亚口腔颌面外科治疗的患者使用下颌前伸矫治器的结果,为该领域的持续实践提供信息。

方法

对 2008 年 1 月至 2014 年 6 月期间因阻塞性睡眠呼吸暂停而接受矫治器治疗的患者的病历进行审核。数据收集包括转诊和人口统计学详细信息、睡眠研究结果、矫治器类型和随访详细信息。

结果

确定了 304 名因阻塞性睡眠呼吸暂停而接受下颌前伸矫治器治疗的患者,其中 82 名患者有诊断性和矫治器在位睡眠研究可供比较。结果观察到,27 名患者有临床意义的客观改善,40 名患者无临床意义的变化,15 名患者在 MAS 治疗后出现临床更严重的 OSA。治疗后每小时呼吸暂停-低通气指数和呼吸障碍指数分别平均减少 8 次(27%)和 13 次(33%)。

结论

基于本研究,下颌前伸矫治器治疗是阻塞性睡眠呼吸暂停患者的一种可行治疗方法。建议采用基于方案的多学科护理,并对结果进行审核。

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