Pennington Zach, Alentado Vincent J, Lubelski Daniel, Alvin Matthew D, Levin Jay M, Benzel Edward C, Mroz Thomas E
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Clin Neurol Neurosurg. 2019 Sep;184:105455. doi: 10.1016/j.clineuro.2019.105455. Epub 2019 Jul 26.
Tandem spinal stenosis (TSS) is a degenerative spinal condition characterized by spinal canal narrowing at 2 or more distinct spinal levels. It is an aging-related condition that is likely to increase as the population ages, but which remains poorly described in the literature. Here we sought to determine the impact of primary lumbar decompression on quality-of-life (QOL) outcomes in patients with symptomatic TSS.
We retrospectively reviewed 803 patients with clinical and radiographic evidence of TSS treated between 2008 and 2014 with a minimum 2-year follow-up. The records of patients with clinical and radiographic evidence of concurrent cervical and lumbar stenosis were reviewed. Prospectively gathered QOL data, including the Pain Disability Questionnaire (PDQ), Patient Health Questionnaire-9 (PHQ-9), EuroQOL-5 Dimensions (EQ-5D), and Visual Analogue Scale (VAS) for low back pain, were assessed at the 6-month, 1-year, and 2-year follow-ups.
Of 803 identified patients (mean age 66.2 years; 46.9% male), 19.6% underwent lumbar decompression only, 14.1% underwent cervical + lumbar decompression, and 66.4% underwent conservative management only. Baseline VAS scores were similar across all groups, but patients undergoing conservative management had better baseline QOL scores on all other measures. Both surgical cohorts experienced significant improvements in the VAS, PDQ, and EQ-5D at all time points; patients in the cervical + lumbar cohort also had significant improvement in the PHQ-9. Conservatively managed patients showed no significant improvement in QOL scores at any follow-up interval.
Lumbar decompression with or without cervical decompression improves low back pain and QOL outcomes in patients with TSS. The decision to prioritize lumbar decompression is therefore unlikely to adversely affect long-term quality-of-life improvements.
串联性椎管狭窄(TSS)是一种退行性脊柱疾病,其特征为在两个或更多不同的脊柱节段出现椎管狭窄。它是一种与年龄相关的疾病,随着人口老龄化可能会增加,但在文献中对此的描述仍然很少。在此,我们试图确定一期腰椎减压对有症状的TSS患者生活质量(QOL)结果的影响。
我们回顾性分析了2008年至2014年间接受治疗且有临床和影像学证据支持TSS的803例患者,随访时间至少为2年。对有颈椎和腰椎狭窄的临床及影像学证据的患者记录进行了审查。在6个月、1年和2年随访时,对前瞻性收集的QOL数据进行评估,包括疼痛残疾问卷(PDQ)、患者健康问卷-9(PHQ-9)、欧洲五维健康量表(EQ-5D)以及下腰痛视觉模拟量表(VAS)。
在803例确诊患者中(平均年龄66.2岁;46.9%为男性),19.6%仅接受了腰椎减压,14.1%接受了颈椎+腰椎减压,66.4%仅接受了保守治疗。所有组的基线VAS评分相似,但接受保守治疗的患者在所有其他测量指标上的基线QOL评分更高。两个手术组在所有时间点的VAS、PDQ和EQ-5D均有显著改善;颈椎+腰椎组的患者在PHQ-9上也有显著改善。保守治疗的患者在任何随访间隔的QOL评分均无显著改善。
无论是否进行颈椎减压,腰椎减压均可改善TSS患者的下腰痛和QOL结果。因此,优先进行腰椎减压的决定不太可能对长期生活质量的改善产生不利影响。