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[慢性尿毒症患者基础及促甲状腺激素释放激素刺激后的促甲状腺激素分泌及总甲状腺素(T4)测定。甲状腺素结合能力及游离甲状腺素指数(FT4-I)]

[Basal and TRH stimulated TSH secretion and determination of total thyroxine (T4). Thyroxine-binding capacity and free thyroxine index (FT4-I) in patients with chronic uremia].

作者信息

Rudolf K, Kunkel S, Rudolf H, Falkenhagen D, Rüting M

机构信息

Klinik für Gynäkologie und Geburtshilfe, Bereichs Medizin, Wilhlem-Pieck-Universität Rostock.

出版信息

Zentralbl Gynakol. 1988;110(11):689-92.

PMID:3137736
Abstract

In 11 patients with chronic uremia both the basal and TRH stimulated TSH levels and T4, TBC and FT4-I were determined. The investigations were repeated in 2 cases after renal transplantation. TSH and T4 in serum were determined by RIA, TBC by radio reagent assay. FT4-I was calculated. In 8 patients the basal TSH levels were in the normo- and in 3 in the hypothyreotropic range. In 9 patients the response to TRH was adequate. There were deviations from the physiological range in 7 patients for T4 and in 6 for FT4-I.

摘要

对11例慢性尿毒症患者测定了基础促甲状腺激素(TSH)水平、促甲状腺激素释放激素(TRH)刺激后的TSH水平以及甲状腺素(T4)、甲状腺结合球蛋白(TBC)和游离甲状腺素指数(FT4-I)。2例患者肾移植后重复进行了这些检查。血清中的TSH和T4通过放射免疫分析(RIA)测定,TBC通过放射试剂法测定。计算FT4-I。8例患者的基础TSH水平在正常范围内,3例在促甲状腺素水平低下范围内。9例患者对TRH的反应正常。7例患者的T4以及6例患者的FT4-I偏离了生理范围。

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