[Behavior of the basal and stimulated serum level of thyroid stimulating hormone and determination of thyroxine, thyroxine- binding capacity and free thyroxine index in females with chronic uremia].

In 11 female patients with chronic uraemia at the age of 20 to 47 years (average age 33.1 years) the basal and the thyrotropin releasing hormone-(TRH-) stimulated thyroid gland stimulating hormone-(SH-) secretion were investigated, in addition to this the parameters of the thyroid gland total thyroxin (T4), thyroxin binding capacity (TBC) as well as the free thyroxin-index (FT4-I). In 2 women the investigations were repeated after kidney transplantation. The determination of TSH and T4 was carried out radioimmunologically, TBC was determined according to the principle of the test tube analysis, whereas FT4-I was established by computation. In 9 of the 11 female patients with chronic uraemia a physiological TSH-response behaviour is existing, whereas for T4 deviations from the reference area are to be stated in 7 female patients and for FT4-I in 6 female patients.