对彭亨布鲁线虫的研究。18. 锑卡醇的驱虫作用。
Studies with Brugia pahangi. 18. Anthelmintic effects of stibocaptate.
作者信息
Denham D A, Suswillo R R, Rogers R
出版信息
J Helminthol. 1978 Sep;52(3):227-8. doi: 10.1017/s0022149x00005423.
PMID:31379
Abstract
Stibocaptate (Asiban, Hoffman--La Roche) killed third stage larvae of Brugia pahangi in vitro at 50 p.p.m. but had no effect on microfilariae at 1 X 10(4) p.p.m No larvae developed in infected mosquitoes fed 1% stibocaptate in 10% sucrose. It was neither micro-nor macrofilaricidal in either jirds or cats but did affect embryogenesis.
摘要
锑卡酯（Asiban，霍夫曼 - 罗氏公司）在体外以50 ppm的浓度可杀死彭亨丝虫的第三期幼虫，但在1×10⁴ ppm时对微丝蚴无作用。用含1%锑卡酯的10%蔗糖溶液喂养感染的蚊子后，没有幼虫发育。它对沙鼠或猫既无杀微丝蚴作用也无杀成虫作用，但会影响胚胎发生。
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