接受重组人γ干扰素治疗的类风湿关节炎患者中抗核抗体的诱导产生
Induction of antinuclear antibodies in patients with rheumatoid arthritis receiving treatment with human recombinant interferon gamma.
作者信息
Seitz M, Franke M, Kirchner H
机构信息
Medizinische Poliklinik, University of Heidelberg, West Germany.
出版信息
Ann Rheum Dis. 1988 Aug;47(8):642-4. doi: 10.1136/ard.47.8.642.
Abstract
Of six patients with rheumatoid arthritis (RA) treated with human recombinant interferon gamma for two to eight months, three developed antinuclear antibodies (ANAs). This was accompanied by a simultaneous clinical exacerbation of the disease activity. In this study both anti-inflammatory and immunostimulatory effects of human recombinant interferon gamma in patients with RA were observed.
摘要
在接受重组人γ干扰素治疗两至八个月的六名类风湿性关节炎（RA）患者中，有三名出现了抗核抗体（ANA）。同时，疾病活动出现了临床加重。在本研究中，观察到了重组人γ干扰素对RA患者的抗炎和免疫刺激作用。
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