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A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria.在有和没有糖尿病的欧洲人群中发现了一种新型罕见的 CUBN 变异体和另外三个基因：一项白蛋白尿的外显子组全基因组关联研究结果。
Diabetologia. 2019 Feb;62(2):292-305. doi: 10.1007/s00125-018-4783-z. Epub 2018 Dec 13.
2
Exposing the exposures responsible for type 2 diabetes and obesity.揭示导致 2 型糖尿病和肥胖的暴露因素。
Science. 2016 Oct 7;354(6308):69-73. doi: 10.1126/science.aaf5094.
3
Genome-wide associations for birth weight and correlations with adult disease.出生体重的全基因组关联及其与成人疾病的相关性。
Nature. 2016 Oct 13;538(7624):248-252. doi: 10.1038/nature19806. Epub 2016 Sep 28.
4
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.更正：年龄和性别对与成人体型和形态的基因关联的影响：一项大规模全基因组相互作用研究。
PLoS Genet. 2016 Jun 29;12(6):e1006166. doi: 10.1371/journal.pgen.1006166. eCollection 2016 Jun.
5
Putting the Genome in Context: Gene-Environment Interactions in Type 2 Diabetes.将基因组置于背景之中：2型糖尿病中的基因-环境相互作用
Curr Diab Rep. 2016 Jul;16(7):57. doi: 10.1007/s11892-016-0758-y.
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Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes.发现影响糖尿病相关血清生物标志物的编码基因变异及其对2型糖尿病风险的影响。
J Clin Endocrinol Metab. 2015 Apr;100(4):E664-71. doi: 10.1210/jc.2014-3677. Epub 2015 Jan 19.
7
Gene × environment interactions in obesity: the state of the evidence.肥胖中的基因×环境相互作用：证据状况
Hum Hered. 2013;75(2-4):106-15. doi: 10.1159/000351070. Epub 2013 Sep 27.
8
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry.基因与身体活动在肥胖中的相互作用：欧洲裔 111421 人的联合分析。
PLoS Genet. 2013;9(7):e1003607. doi: 10.1371/journal.pgen.1003607. Epub 2013 Jul 25.
9
Challenges and opportunities in genome-wide environmental interaction (GWEI) studies.全基因组环境交互作用（GWEI）研究中的挑战与机遇。
Hum Genet. 2012 Oct;131(10):1591-613. doi: 10.1007/s00439-012-1192-0. Epub 2012 Jul 4.
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Recommendations and proposed guidelines for assessing the cumulative evidence on joint effects of genes and environments on cancer occurrence in humans.关于评估基因和环境对人类癌症发生的联合效应的累积证据的建议和拟议准则。
Int J Epidemiol. 2012 Jun;41(3):686-704. doi: 10.1093/ije/dys010. Epub 2012 May 16.

Editorial: The Role of Genetic and Lifestyle Factors in Metabolic Diseases.

作者信息

Ahmad Shafqat, Ahluwalia Tarunveer S

机构信息

Molecular Epidemiology Unit, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

Preventive Medicine Division, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, United States.

出版信息

Front Endocrinol (Lausanne). 2019 Jul 17;10:475. doi: 10.3389/fendo.2019.00475. eCollection 2019.

DOI:10.3389/fendo.2019.00475
PMID:31379743
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6650930/
Abstract
摘要