Kavvalou Eirini, Stefanidou Maria, Krueger-Krasagakis Sabine Elke, Evangelou George, Koumaki Dimitra, Marinos Leonidas, Tzardi Maria, Krasagakis Konstantinos
Department of Dermatology, University General Hospital of Heraklion, 71500 Heraklion, Greece.
Department of Haematopathology, Evaggelismos General Hospital of Athens, Ipsilantou 45-47, 10676, Athens, Greece.
Case Rep Dermatol Med. 2019 Jul 16;2019:1765210. doi: 10.1155/2019/1765210. eCollection 2019.
This is the case of a 27-year-old male patient with a newly diagnosed extensive lymphomatoid papulosis type A involving cosmetically sensitive areas (e.g. face), who refused to be treated with a low dose of methotrexate, as recommended by the published literature. The natural course of the disease was proved to be strikingly satisfying though, with a complete regression of all skin lesions at the 4-week follow-up, including an ulcerated nodule 3 x 3 cm in dimension, which was expected to heal at least in months. We report this case to reconsider weighting the risks and the short-term benefits of methotrexate treatment, even in the case of an extensive disease.
这是一名27岁男性患者的病例，他新诊断为广泛性A型淋巴瘤样丘疹病，累及美容敏感区域（如面部），该患者拒绝按照已发表文献的建议接受低剂量甲氨蝶呤治疗。不过，事实证明该疾病的自然病程非常令人满意，在4周的随访中所有皮肤损害完全消退，包括一个3×3厘米的溃疡结节，预计至少需要数月才能愈合。我们报告此病例，以重新权衡甲氨蝶呤治疗的风险和短期益处，即使是在广泛性疾病的情况下。
