Ghosn Youssef, Abdallah Ali, Hussein Kamareddine Mohammed, Geahchan Amine, Baghdadi Ahmad, El-Rassi Ziad, Chamseddine Abbas, Ashou Raja
Faculty of Medicine and Medical Sciences, University of Balamand, Achrafieh, Beirut, Lebanon.
Department of Diagnostic Radiology, Saint George Hospital University Medical Center, University of Balamand, Achrafieh, Beirut, Lebanon.
Case Reports Hepatol. 2019 Jul 16;2019:5274525. doi: 10.1155/2019/5274525. eCollection 2019.
A 38-year-old diabetic woman, with history of cholecystectomy and ventral hernia repair, was hospitalized due to sudden-onset abdominal pain and fever. Computed tomography revealed a mixed collection containing necrotic debris and emphysematous change in the left lobe of the liver mainly in segments II and III. These radiological findings suggested emphysematous hepatitis (EH). The patient's condition deteriorated rapidly, and she was rushed to the operating room for urgent exploratory laparotomy where debridement was performed. Intraoperatively the patient was found to have an abscess with incomplete capsule concurrent with hepatic necrosis suggesting the co-occurrence of abscess and EH. The patient survived and was discharged after 13 days. Relevant literature was reviewed, and to the best of our knowledge, EH is an extremely rare entity with limited data regarding its pathogenesis, causative organisms, and management. EH is a rapidly invasive disease process that can be fatal if appropriate therapeutic intervention is delayed. Initial presentations are usually subtle, thus high clinical and radiological suspicion is required for early diagnosis and management to decrease associated mortality and morbidity. We hence report the first successfully treated case of EH with review of the literature.
一名38岁的糖尿病女性,有胆囊切除术和腹疝修补病史,因突发腹痛和发热入院。计算机断层扫描显示肝脏左叶(主要在II段和III段)有一个包含坏死碎片的混合性积液以及气肿性改变。这些影像学表现提示为气肿性肝炎(EH)。患者病情迅速恶化,被紧急送往手术室进行急诊剖腹探查术并进行了清创。术中发现患者有一个包膜不完整的脓肿,同时伴有肝坏死,提示脓肿和气肿性肝炎并存。患者存活,13天后出院。我们查阅了相关文献,据我们所知,气肿性肝炎是一种极其罕见的疾病,关于其发病机制、致病微生物和治疗的资料有限。气肿性肝炎是一种迅速侵袭性的疾病过程,如果延迟适当的治疗干预可能会致命。初始表现通常不明显,因此早期诊断和治疗需要高度的临床和影像学怀疑,以降低相关的死亡率和发病率。因此,我们报告了首例成功治疗的气肿性肝炎病例并对文献进行了综述。