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洗必泰过敏:在医疗环境中,轻度过敏反应可能先于过敏反应发生。

Chlorhexidine Allergy: Mild Allergic Reactions Can Precede Anaphylaxis in the Healthcare Setting.

作者信息

Opstrup Morten Schjørring, Garvey Lene Heise

机构信息

Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.

Danish Anaesthesia Allergy Centre, Allergy Clinic, Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte, Gentofte, Denmark.

出版信息

Turk J Anaesthesiol Reanim. 2019 Aug;47(4):342-344. doi: 10.5152/TJAR.2019.22058. Epub 2019 Mar 12.

DOI:10.5152/TJAR.2019.22058
PMID:31380516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6645843/
Abstract

Chlorhexidine can cause severe immediate-type allergic reactions such as urticaria, anaphylactic shock or, even, cardiac arrest. We report the case of a patient who developed perioperative anaphylactic shock caused by chlorhexidine 1 year after a postoperative urticarial reaction, which was assumed not to be significant at the time. This case highlights the importance of identifying mild allergy symptoms after exposure to chlorhexidine at the pre-anaesthetic assessment to prevent more severe allergic reactions in future.

摘要

洗必泰可引起严重的速发型过敏反应,如荨麻疹、过敏性休克,甚至心脏骤停。我们报告一例患者,该患者在术后出现荨麻疹反应1年后,在围手术期发生了由洗必泰引起的过敏性休克,当时认为该荨麻疹反应不严重。该病例强调了在麻醉前评估时识别接触洗必泰后出现的轻度过敏症状的重要性,以防止未来发生更严重的过敏反应。

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引用本文的文献

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本文引用的文献

1
Anaesthesia, surgery, and life-threatening allergic reactions: epidemiology and clinical features of perioperative anaphylaxis in the 6th National Audit Project (NAP6).麻醉、手术和危及生命的过敏反应:第 6 次国家审计项目(NAP6)中围手术期过敏反应的流行病学和临床特征。
Br J Anaesth. 2018 Jul;121(1):159-171. doi: 10.1016/j.bja.2018.04.014. Epub 2018 May 21.
2
Chlorhexidine allergy: sources of exposure in the health-care setting.洗必泰过敏:医疗机构中的接触源
Br J Anaesth. 2015 Apr;114(4):704-5. doi: 10.1093/bja/aev050.
3
Clinical and diagnostic features of perioperative hypersensitivity to cefuroxime.
Clin Exp Allergy. 2015 Apr;45(4):807-14. doi: 10.1111/cea.12455.
4
Standardized testing with chlorhexidine in perioperative allergy--a large single-centre evaluation.围手术期过敏中氯己定的标准化检测——一项大型单中心评估。
Allergy. 2014 Oct;69(10):1390-6. doi: 10.1111/all.12466. Epub 2014 Aug 13.
5
Preoperative chlorhexidine anaphylaxis in a patient scheduled for coronary artery bypass graft: a case report.一例计划进行冠状动脉旁路移植术患者的术前氯己定过敏反应:病例报告
AANA J. 2013 Jun;81(3):209-14.
6
Skin test concentrations for systemically administered drugs -- an ENDA/EAACI Drug Allergy Interest Group position paper.皮下注射药物的浓度——ENDA/EAACI 药物过敏兴趣小组立场文件。
Allergy. 2013 Jun;68(6):702-12. doi: 10.1111/all.12142. Epub 2013 Apr 25.
7
Immediate hypersensitivity to chlorhexidine is increasingly recognised in the United Kingdom.在英国,对氯己定的速发型超敏反应越来越受到关注。
Allergol Immunopathol (Madr). 2014 Jan-Feb;42(1):44-9. doi: 10.1016/j.aller.2012.08.001. Epub 2012 Dec 20.
8
Anaphylaxis to chlorhexidine-coated central venous catheters: a case series and review of the literature.氯己定涂层中心静脉导管过敏反应:病例系列及文献复习。
Surg Infect (Larchmt). 2012 Jun;13(3):171-4. doi: 10.1089/sur.2011.011. Epub 2012 May 8.
9
Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.氯己定-酒精与聚维酮碘用于手术部位消毒。
N Engl J Med. 2010 Jan 7;362(1):18-26. doi: 10.1056/NEJMoa0810988.
10
IgE-mediated allergy to chlorhexidine.对氯己定的IgE介导的过敏反应。
J Allergy Clin Immunol. 2007 Aug;120(2):409-15. doi: 10.1016/j.jaci.2007.04.029. Epub 2007 Jun 7.