Al Dehailan Anas S
King Fahad Hospital of the University, AL Khobar, Imam Abdul Rahman Bin Faisal University, Kingdom of Saudi Arabia. E-mail:
Neurosciences (Riyadh). 2019 Jul;24(3):236-239. doi: 10.17712/nsj.2018.3.20190025.
Tremor is the most common and frequently reported movement disorder in multiple sclerosis (MS). Paroxysmal dystonia (PD), also known as painful tonic spasm (PTS), is a relatively less common but well-recognized movement disorder in multiple sclerosis (MS). These are characterized by episodic attacks of involuntary flexion, extension movements of body. Such paroxysmal symptoms as an initial presenting feature raise many differential diagnoses and can often be mistaken as epileptic seizures as well as psychogenic events and may sometimes lead to delay in diagnosis as well. Diagnosis is clinical with the help of supportive investigations to rule out other paroxysmal disorders, especially epileptic seizures. We describe a case of a young lady, who was referred to us as a case of refractory seizure and diagnosed as having paroxysmal dystonia as a first manifestation of MS, with complete resolution of her symptoms after successful treatment with anti-epileptic drugs.
震颤是多发性硬化症（MS）中最常见且报道频繁的运动障碍。阵发性肌张力障碍（PD），也称为疼痛性强直性痉挛（PTS），是多发性硬化症（MS）中相对少见但已被充分认识的运动障碍。这些疾病的特征是身体出现不由自主的屈伸运动的发作性发作。这种作为初始表现特征的阵发性症状引发了许多鉴别诊断，并且常常被误诊为癫痫发作以及心因性事件，有时还可能导致诊断延迟。诊断依靠临床检查并借助支持性检查来排除其他阵发性疾病，尤其是癫痫发作。我们描述了一位年轻女性的病例，她最初被转诊至我们这里时被诊断为难治性癫痫发作，最终被诊断为阵发性肌张力障碍，这是她多发性硬化症的首发表现，在成功使用抗癫痫药物治疗后症状完全缓解。
