在德国莱茵-美因大都市区，万古霉素耐药的 ST117/CT71/B- 克隆几乎无处不在。
Near-ubiquitous presence of a vancomycin-resistant ST117/CT71/B -clone in the Rhine-Main metropolitan area of Germany.
机构信息
1Institute of Medical Microbiology, Justus Liebig University Giessen and German Center for Infection Research (DZIF), Partner Site Giessen-Marburg-Langen, Schubertstrasse 81, 35392 Giessen, Germany.
Rhine-Main- Network on MDRO (multidrug-resistant organisms), Breite Gasse 28, 60313 Frankfurt/Main, Germany.
出版信息
Antimicrob Resist Infect Control. 2019 Jul 29;8:128. doi: 10.1186/s13756-019-0573-8. eCollection 2019.
Whole-genome sequencing analysis of Vancomycin-resistant isolates from the Frankfurt metropolitan region revealed that 78/94 isolates were MLST type ST117, cgMLST complex type CT71 with a common B chromosomal insertion site. This indicates circulation of a single VRE clone in a catchment area of 5,000-km with 3 million inhabitants.
对来自法兰克福大都市区的万古霉素耐药分离株进行全基因组测序分析表明，94 株分离株中有 78 株为 ST117 型 MLST、CT71 型 cgMLST 复合体，具有共同的 B 染色体插入位点。这表明在一个拥有 300 万居民、面积达 5000 平方公里的集水区中，存在一种单一的 VRE 克隆的传播。
Zotero 插件