肠道微生物群在脑功能及应激相关病理学中的作用。
Role of gut microbiota in brain function and stress-related pathology.
作者信息
Sudo Nobuyuki
机构信息
1Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
出版信息
Biosci Microbiota Food Health. 2019;38(3):75-80. doi: 10.12938/bmfh.19-006. Epub 2019 Apr 25.
Abstract
Gut microbiota are responsible for a variety of metabolic activities including food digestion and production of biologically active substances. Moreover, several recent works, including our own, have also shown that gut microbiota play an important role not only in the development of brain function but also in the pathology of stress-related diseases and neurodevelopmental disorders. In this review, we focus on the interaction between gut microbes and the brain-gut axis and introduce some basic concepts and recent developments in this area of research.
摘要
肠道微生物群负责多种代谢活动，包括食物消化和生物活性物质的产生。此外，包括我们自己的研究在内，最近的几项研究还表明，肠道微生物群不仅在脑功能发育中发挥重要作用，而且在应激相关疾病和神经发育障碍的病理学中也发挥重要作用。在这篇综述中，我们聚焦于肠道微生物与脑-肠轴之间的相互作用，并介绍该研究领域的一些基本概念和最新进展。
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