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泰国化妆品致发用化妆品变应原接触过敏。

Contact allergy to hair cosmetic allergens in Thailand.

机构信息

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Contact Dermatitis. 2019 Dec;81(6):426-431. doi: 10.1111/cod.13373. Epub 2019 Aug 21.

Abstract

BACKGROUND

Hair cosmetics such as hair dyes, bleaching, waving, and cleansing products are composed of numerous chemical ingredients. Allergic reactions to these contact allergens, other than p-phenylenediamine, are rarely reported.

OBJECTIVES

To study the incidence of patch test reactions to hair cosmetic allergens and identify the factors associated with hair cosmetic allergy in Thailand.

METHODS

We retrospectively reviewed the case records of patients who underwent patch testing from 2009 to 2018. Patients with at least one positive patch test reaction to a potential contact allergen associated with hair cosmetic ingredients were studied.

RESULTS

Overall, 2842 patients were patch tested. Of the hair cosmetic allergen categories, preservatives had the highest rate of positive reactions, followed by surfactants and hair dyes. Perming agents were less problematic in comparison. The hands, head, and neck were the predominately affected sites of allergic reactions to hair cosmetic ingredients.

CONCLUSIONS

Preservatives, surfactants, and hair dyes are important contact allergens, whereas perming agents are less likely to cause allergic reactions. Hair cosmetic ingredients are regulated by national agencies, which influences their extent of exposure and rates of contact allergies. Further continuous observation of hair cosmetic allergy is needed to provide the best patient care.

摘要

背景

头发化妆品,如染发剂、漂白剂、烫发剂和清洁产品,由众多化学成分组成。除了对苯二胺之外,这些接触性过敏原很少引起过敏反应。

目的

研究接触性毛发化妆品过敏原的斑贴试验反应发生率,并确定与泰国毛发化妆品过敏相关的因素。

方法

我们回顾性地分析了 2009 年至 2018 年间接受斑贴试验的患者的病例记录。研究对象为至少有一种与毛发化妆品成分相关的潜在接触性过敏原的阳性斑贴试验反应患者。

结果

共有 2842 名患者接受了斑贴试验。在毛发化妆品过敏原类别中,防腐剂的阳性反应率最高,其次是表面活性剂和染发剂。烫发剂的问题较少。手部、头部和颈部是毛发化妆品成分引起过敏反应的主要部位。

结论

防腐剂、表面活性剂和染发剂是重要的接触性过敏原,而烫发剂则不太可能引起过敏反应。毛发化妆品成分受国家机构监管,这影响了它们的暴露程度和接触过敏的发生率。需要对毛发化妆品过敏进行进一步的持续观察,以提供最佳的患者护理。

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