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[Structure and antipyretic-hypothermizing effect of various pyrazol/1,5-a/pyrimidines].

作者信息

Auzzi G, Cecchi L, Costanzo A, Pecori Vettori L, Bruni F, Pirisino R, Ciottoli G B

出版信息

Farmaco Sci. 1979 Jun;34(6):478-85.

PMID:313884
Abstract

Structures of condensation products between 3-phenyl-5-aminopyrazole and ethyl ethoxymethylenacetoacetate and ethyl acetonoxalate are demonstrated, namely ethyl 2-phenyl-7-methylpyrazolo[1,5-a]pyrimidin-6-carboxylate and ethyl 2-phenyl-7-methylpyrazolo[1,5-a]pyrimidin-5-carboxylate. Studies on antipyretic and hypothermizing activity of the acid derived from the latter and of other compounds are reported.

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