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[Structure and antipyretic-hypothermizing effect of various pyrazol/1,5-a/pyrimidines].

作者信息

Auzzi G, Cecchi L, Costanzo A, Pecori Vettori L, Bruni F, Pirisino R, Ciottoli G B

出版信息

Farmaco Sci. 1979 Jun;34(6):478-85.

PMID:313884
Abstract

Structures of condensation products between 3-phenyl-5-aminopyrazole and ethyl ethoxymethylenacetoacetate and ethyl acetonoxalate are demonstrated, namely ethyl 2-phenyl-7-methylpyrazolo[1,5-a]pyrimidin-6-carboxylate and ethyl 2-phenyl-7-methylpyrazolo[1,5-a]pyrimidin-5-carboxylate. Studies on antipyretic and hypothermizing activity of the acid derived from the latter and of other compounds are reported.

摘要

相似文献

1
[Structure and antipyretic-hypothermizing effect of various pyrazol/1,5-a/pyrimidines].
Farmaco Sci. 1979 Jun;34(6):478-85.
2
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Farmaco. 1993 Jul;48(7):949-66.
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Farmaco Sci. 1981 Jun;36(6):441-8.
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[Synthesis of pyrazole derivatives and pyrazolo[4,3-d]pyrimidines. I].
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Synthesis and anti-inflammatory activity of some [4,6-(4-substituted aryl)-2-thioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl]-acetic acid derivatives.某些[4,6-(4-取代芳基)-2-硫代-1,2,3,4-四氢嘧啶-5-基]乙酸衍生物的合成及其抗炎活性
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3,5-Diphenyl-1H-pyrazole derivatives. IX. 2-substituted 4-phenyl-5-(3,5-diphenyl-1H-pyrazol-1-yl) pyrimidines with platelet antiaggregating and other activities.3,5-二苯基-1H-吡唑衍生物。IX。具有血小板抗聚集及其他活性的2-取代-4-苯基-5-(3,5-二苯基-1H-吡唑-1-基)嘧啶
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1-phenyl-1H-pyrazole derivatives with antiinflammatory, analgesic and antipiretic activities.具有抗炎、镇痛和解热活性的1-苯基-1H-吡唑衍生物。
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Facile synthesis of fused pyrazolo[1,5-a]pyrimidinepyrazolo [1,5-a]triazines and N-sulphonamidopyrazoles as antiinflammatory.简便合成稠合吡唑并[1,5-a]嘧啶并吡唑并[1,5-a]三嗪和N-磺酰胺基吡唑作为抗炎剂。
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[Condensation of 3-phenyl-5-aminopyrazolo with acylpyruvic and ethoxymethylenacetic esters].[3-苯基-5-氨基吡唑与酰基丙酮酸酯和乙氧基亚甲基乙酸酯的缩合反应]
Farmaco Sci. 1979 Oct;34(10):898-906.

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