Auzzi G, Cecchi L, Costanzo A, Pecori Vettori L, Bruni F
Farmaco Sci. 1979 Oct;34(10):898-906.
The synthesis of ethyl 2-phenyl-7-alkyl (or 7-phenyl)pyrazolo[1,5-a]pyrimidine-5-carboxylate and ethyl 2-phenyl-7-alkyl (or 7-phenyl)pyrazolo[1.5-a]pyrimidine-6-carboxylate are reported. Decarboxylation of the acids, obtained by hydrolysis of the above esters, yields the same compounds. N.M.R. data on the reduction products of the ethyl 6-carboxylate confirm all the assigned structures.
报道了2-苯基-7-烷基(或7-苯基)吡唑并[1,5-a]嘧啶-5-羧酸乙酯和2-苯基-7-烷基(或7-苯基)吡唑并[1.5-a]嘧啶-6-羧酸乙酯的合成。上述酯水解得到的酸经脱羧反应生成相同的化合物。关于6-羧酸乙酯还原产物的核磁共振数据证实了所有指定的结构。