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979 例开放性脐疝修补术后复发的预测因素。

Predictors for recurrence after open umbilical hernia repair in 979 patients.

机构信息

Department of Surgery, NorthShore University HealthSystem, Evanston, IL.

Department of Surgery, NorthShore University HealthSystem, Evanston, IL.

出版信息

Surgery. 2019 Oct;166(4):615-622. doi: 10.1016/j.surg.2019.04.040. Epub 2019 Aug 7.

Abstract

BACKGROUND

Our study aims were to evaluate factors that predict recurrence after open umbilical hernia repair with either mesh or primary closure.

METHODS

Consecutive patients (n = 1,125) undergoing open umbilical hernia repair from 2009 to 2018 were identified from a prospectively managed, quality database. Kaplan-Meier curves and log-rank tests were used to analyze recurrence-free survival for preoperative, intraoperative, and postoperative factors. Univariable and multivariable Cox regression was used to analyze recurrence-free survival by age, sex, body mass index, concurrent laparoscopic inguinal hernia repair, smoking status, diabetes, postoperative infection, hernia size in greatest dimension, and type of repair.

RESULTS

The overall recurrence rate was 3.3% with a median follow-up of 14 months. Univariable analysis revealed a difference in recurrence-free survival for current smoking (P = .039), diabetes (P = .007), higher body mass index (P = .057), and postoperative infection (P < .001). Multivariable analysis indicated higher body mass index (P = .007), concurrent laparoscopic inguinal hernia repair (P = .044), current smoking status (P = .020), diabetes (P = .021), and a primary closure repair of hernias ≥1.5 cm (P = .001) had a greater risk of recurrence. Postoperative infection showed an association with recurrence (P = .053).

CONCLUSION

Our results indicate higher body mass index, concurrent laparoscopic inguinal hernia repair, current smoking, diabetes, primary closure repair of hernias ≥1.5 cm, and postoperative infection were associated with a greater risk of recurrence after open umbilical hernia repair.

摘要

背景

本研究旨在评估接受开放脐疝修补术(使用网片或直接缝合)后复发的预测因素。

方法

从一个前瞻性管理的质量数据库中确定了 2009 年至 2018 年间连续接受开放脐疝修补术的患者(n=1125)。Kaplan-Meier 曲线和对数秩检验用于分析术前、术中及术后因素对无复发生存率的影响。单变量和多变量 Cox 回归用于分析年龄、性别、体重指数、同期腹腔镜腹股沟疝修补术、吸烟状态、糖尿病、术后感染、疝最大径、修补类型等因素对无复发生存率的影响。

结果

总的复发率为 3.3%,中位随访时间为 14 个月。单变量分析显示,吸烟状态(P=0.039)、糖尿病(P=0.007)、较高的体重指数(P=0.057)和术后感染(P<0.001)对无复发生存率有影响。多变量分析表明,较高的体重指数(P=0.007)、同期腹腔镜腹股沟疝修补术(P=0.044)、当前吸烟状态(P=0.020)、糖尿病(P=0.021)和疝直径≥1.5cm 的直接缝合修补术(P=0.001)的复发风险更高。术后感染与复发有关(P=0.053)。

结论

我们的研究结果表明,体重指数较高、同期腹腔镜腹股沟疝修补术、当前吸烟状态、糖尿病、疝直径≥1.5cm 的直接缝合修补术以及术后感染与开放脐疝修补术后复发风险增加相关。

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