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多中心前瞻性观察研究格拉斯哥入院预测评分与不良结局的相关性。

Multicentre, prospective observational study of the correlation between the Glasgow Admission Prediction Score and adverse outcomes.

机构信息

School of Health and Related Research, University of Sheffield, Sheffield, UK

Acute Medicine, Glasgow Royal Infirmary, Glasgow, UK.

出版信息

BMJ Open. 2019 Aug 10;9(8):e026599. doi: 10.1136/bmjopen-2018-026599.

Abstract

OBJECTIVES

To assess whether the Glasgow Admission Prediction Score (GAPS) is correlated with hospital length of stay, 6-month hospital readmission and 6-month all-cause mortality. This study represents a 6-month follow-up of patients who were included in an external validation of the GAPS' ability to predict admission at the point of triage.

SETTING

Sampling was conducted between February and May 2016 at two separate emergency departments (EDs) in Sheffield and Glasgow.

PARTICIPANTS

Data were collected prospectively at triage for consecutive adult patients who presented to the ED within sampling times. Any patients who avoided formal triage were excluded from the study. In total, 1420 patients were recruited.

PRIMARY OUTCOMES

GAPS was calculated following triage and did not influence patient management. Length of hospital stay, hospital readmission and mortality against GAPS were modelled using survival analysis at 6 months.

RESULTS

Of the 1420 patients recruited, 39.6% of these patients were initially admitted to hospital. At 6 months, 30.6% of patients had been readmitted and 5.6% of patients had died. For those admitted at first presentation, the chance of being discharged fell by 4.3% (95% CI 3.2% to 5.3%) per GAPS point increase. Cox regression indicated a 9.2% (95% CI 7.3% to 11.1%) increase in the chance of 6-month hospital readmission per point increase in GAPS. An association between GAPS and 6-month mortality was demonstrated, with a hazard increase of 9.0% (95% CI 6.9% to 11.2%) for every point increase in GAPS.

CONCLUSION

A higher GAPS is associated with increased hospital length of stay, 6-month hospital readmission and 6-month all-cause mortality. While GAPS's primary application may be to predict admission and support clinical decision making, GAPS may provide valuable insight into inpatient resource allocation and bed planning.

摘要

目的

评估格拉斯哥入院预测评分(GAPS)与住院时间、6 个月内再入院和 6 个月内全因死亡率的相关性。本研究是对 GAPS 在分诊点预测入院能力进行外部验证的患者进行的 6 个月随访。

设置

于 2016 年 2 月至 5 月在谢菲尔德和格拉斯哥的两个独立急诊部(ED)进行抽样。

参与者

在抽样时间内连续向 ED 就诊的成年患者在分诊时前瞻性收集数据。任何避免正式分诊的患者均被排除在研究之外。共招募了 1420 名患者。

主要结局

分诊后计算 GAPS,不影响患者管理。使用生存分析在 6 个月时对住院时间、6 个月内再入院和死亡率与 GAPS 进行建模。

结果

在 1420 名招募的患者中,39.6%的患者最初住院。6 个月时,30.6%的患者再次入院,5.6%的患者死亡。对于首次就诊时入院的患者,GAPS 每增加 1 分,出院的机会就会下降 4.3%(95%CI 3.2%至 5.3%)。Cox 回归表明,GAPS 每增加 1 分,6 个月内再入院的机会就会增加 9.2%(95%CI 7.3%至 11.1%)。表明 GAPS 与 6 个月死亡率之间存在关联,GAPS 每增加 1 分,危险比增加 9.0%(95%CI 6.9%至 11.2%)。

结论

较高的 GAPS 与住院时间延长、6 个月内再入院和 6 个月内全因死亡率增加相关。虽然 GAPS 的主要应用可能是预测入院并支持临床决策,但 GAPS 可能为住院资源分配和床位规划提供有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17ec/6701614/cf6e1002a0a9/bmjopen-2018-026599f01.jpg

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